Bone Path 3 Flashcards
Metabolic bone diseases
Richitic rosary / osteomalacia
Inflammatory bone disease
Non-infectious bone disease
Proliferation non neoplastic lesions
Hypertrophic osteopathy
Primary bone neoplasia
Secondary bone neoplasia
Multilobular osteosarcoma
Rickets vs osteomalacia
Rickets is found in young animals who’s physis has not sealed yet
Osteomalacia is in older animals whos physis has sealed
Pathogenesis of rickets/osteomalacia
Failure of mineralization
Accumulation of osteoids
Bone deformities, path fractures
Common for Vit d or phos deficiency
path of rickets
Bone & growth plate cartilage is effected
Failure of endochondral ossification = thickened growth plates
Path of osteomalacia
Adults
Failure of bone mineralization
Impaired bone remodeling
Causes for inflammatory bone diseases
Bacteria > fungal, virus, parasitic
Terminology for inflammatory bone diseases
Osteitis - inflammation of bone
Osteomyelitis - inflammation of medullary bone
Periostitis - inflammation of outer bone
Pathogenesis of osteomyelitis in vertebral column
Initial FPT - sepsis - septicemia - bacterial osteomyelitis
Hypertrophic osteosydrophy
Non infection inflammatory disease
Metaphyseal osteopathy
Common in young large breed dogs
Lesion of hypertrophic osteodystrophy
Suppurative (neutrophils) osteomyelitis of metaphysis of long bones
Presents as lameness, swollen metaphyses
Periosteum new bone formation is common in chronic cases
Causes for hypertrophic osteodystrophy
Unknown
Infectious causes suspected
Hypertrophic ostepathy
Pulmonary osteopathy - neoplastic disease
Bilateral progressive periosteum new bone proliferation. Occurs in diaphysis and metaphysis
Common in long bones & dogs
Hypertrophic osteopathy is commonly a secondary reaction to
Pulmonary or Intra thoracic neoplasms or inflammation
Less common causes, endocarditis, heart worms disease, urinary bladder neoplasia
Pathogenesis of hypertrophic ostepathy
Not 100%
Could result from vagus nerve mediated increased blood flow to periosteum =new growth
