Bone And Soft Tissue Flashcards
Joints
A point where 2 separate bones meet
MSk system is made up of what
Bone
Muscle
Connective tissue ( tendon , ligaments, cartilage)
How many bones in adults
206 and sesamoids
How many bones in children
270
Appendicular Skelton
Pectoral girdle
Upper and lower limbs
Pelvic girdle
Axial skeleton
Cranium
Vertebral column
Rib cage
Functions of skeleton
Support Protect vital organs Movement - works with muscles Mineral storage ( stores calcium and phosphate) Produces blood cells ( bone marrow)
How do flat bones develop 8n uterine
Intramembranous ossification
How do long bones develop in utero
Endochondral ossification
Flat bones
Skull
Clavicle
Mandible
Process of untramembranous ossification ( mesenchymal to bone )
Mesenchymal cells condense
Osteogenesic precursor cells prolif
Precursor cells differentiate into osteoblasts
Osteoblasts form ossification centres and begin to secrete Osteoid
( trapped osteoblasts become osteocytes)
Osteoid become mineralised
Trabecular matrix and periosteum forms
Compact bone develops superficial to cancellous bone
Crowded blood vessels condense into red bone marrow
Endochondral ossification
Mesenchymal cells aggregate
Formation of cartilage model
Bone collar and primary ossification centre in diaphysis develop
Fuormation of marrow cavity
Epiphyseal cartilage comenses ossification
Ossification of lower epiphyseal plate commences
Disappearance of epiphyseal cartilage - cessation of bone growth
Which form on embryo logical bone growth takes longer
Endochondral
What are bones made up of
Cells and matrix
Bone cells
Osteogenic
Osteoblasts
Osteoclasts
Osteocytes
Osteogenic
Bone stem cell
Found in deep layers of periosteum ( outer part of bone)
Osteoblasts
Bone forming
Secrets Osteoid
Catalyse mineralisation of Osteoid
Growing portions of bone , including periosteum and endosteum
Osteoclast
Bone breaking
Dissolve and resorb bone by phagocytosis
Found at bone surfaces and at sites of old , injured or unneeded bone