Bone Flashcards

1
Q

what are the functions of bone?

A

Support, Locomotion, Protection, Haematopoiesis, Mineral storage, Acid-base balance, Detoxification

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2
Q

what are the sections of bone?

A
Epiphysis= ends of long bones.
Diaphysis= shaft of long bones.
Metaphysis= between the other two
articular cartilage at ends
periosteum covering outside
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3
Q

what is spongy bone composed of?

A

trabeculae which branch and intersect

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4
Q

what surrounds bone?

A

a layer of dense connective tissue, the periosteum

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5
Q

what are the bone forming cells?

A

osteoblasts

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6
Q

where are osteoblasts found?

A

the periosteum and the endosteum which possess osteogenic potency

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7
Q

what is a haversian system?

A

lamellae and central canals

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8
Q

what is found between lacunae?

A

canaliculi

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9
Q

does spongy bone contain haversian systems?

A

no

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10
Q

what does the yellow marrow in spongy bone consist of?

A

adipose tissue

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11
Q

what is osteoporosis?

A

A disease characterized by low bone mass and micro architectural deterioration of bone tissue, leading to enhanced bone fragility and an increase In fracture risk

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12
Q

what are osteoblasts?

A

immature bone cells that synthesize osteoid and mediate mineralisation

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13
Q

what do osteocytes release?

A

calcium for homeostasis

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14
Q

what controls osteocyte activity?

A

calcium levels, parathyroid and calcitonin

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15
Q

what are osteocytes?

A

inactive osteoblasts

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16
Q

what is an osteoclast?

A

a large phagocytic cell with many mitochondria and lysozymes which break down bone matrix

17
Q

what stimulates osteoclasts?

A

parathyroid hormone

18
Q

what inhibits osteoclasts?

A

calcitonin

19
Q

what are the processes of osteogenesis?

A
  1. intramembranous ossification

2. endochondral ossification

20
Q

what is intramembranous ossification?

A

replacement of connective tissue sheets with bone tissue ie Flat bones

21
Q

what is endochondral ossification?

A

replacement of a hyaline cartilage model with bone tissue ie Long bones