Blood Types (ASAN002/17) Flashcards
Canine Blood Types
Over 15 canine blood groups have been described.\nOnly 8 types are recognised at international standards.\nAcronym DEA & a number are used to identify canine blood type.
DEA
Dog Erythrocyte Antigen
Recongised Canine Blood Types:
DEA – 1.1\nDEA – 1.2\nDEA – 3\nDEA – 4\nDEA – 5\nDEA – 6\nDEA – 7\nDEA – 8
Most important canine blood type:
DEA 1.1
DEA 1.1 +ve Canines
33 – 45 %\nConsidered to be Universal Recipients– can receive any blood type without fear of life–threatening transfusion.
DEA 1.1 negative Canines
Considered to be Universal Donors\nDEA 1.1 neg dogs should NEVER be given DEA 1.1 +ve blood.
First blood transfusion –
Transfused cells have a shortened life span\nAlloantibodies will be formed – making the dog forever sensitive to DEA 1.1 blood\nIf another blood transfusion is given, life–threatening reactions can occur.
Alloantiboidies
Formed at first blood transfusion.\nIs one that naturally occurs against tissues (e.g. blood cell proteins) from an animal of same species.\nNaturally occurring means they don’t need to have been previously exposed to the antigen.
Feline Blood Types
Identified as:\nA\nB\nAB (extremely rare)
Must blood type cats prior to transfusion.
They will have alloantibodies against the other blood type.
Type B cats
Have strong naturally occurring antibodies against Type A blood.\nEven a small amt (1ml) can cause a fatal reaction.
Type A cats
Have weak alloantibodies against Type B cats.\nIf Type B blood is given to Type A cat, the half–life of RBC’s is reduced & the transfusion is clinically ineffective – the RBC’s functional time is so short (2days).
Type B – most common breeds:
British Shorthair = 40%\nCornish Rex = 34%\nDevon Rex = 41%
Type A – breeds found to be nearly 100% this type:
Siamese\nBurmese\nTonkinese
Prior to blood transfusing cats:
Cats must always be typed &/or cross matched prior to transfusion.