Blood Disorders

Question 1

Anemia : oral manifestations

Answer 1

pallor, angular cheilitis, erythema/atrophy of oral mucosa, loss of filiform/fungiform papillae on dorsum of tongue

Question 2

Iron Deficient Anemia

Answer 2

not enough iron supplied to bone marrow for RBC development

menstrual bleeding, gastro bleeding, poor iron absorption, pregnancy/infancy

Question 3

Pernicious Anemia

Answer 3

deficiency of intrinsic factor (parietal cells in stomach) > absorption of B12 affected

Question 4

Folic Acid / B12 Anemia

Answer 4

dietary deficiencies/malnutrition > alcoholism/pregnancy

Question 5

Thalassemia (Mediteranean or Cooley) Anemia

Answer 5

inherited disorders of hemoglobin synthesis. can be major or minor. “salt n pepper” radiographs

Question 6

Sickle Cell Anemia

Answer 6

RBS have sickle shape with decreased Oxygen
inherited
black, women, under 30yo

Question 7

Sickle Cell: clinically

Answer 7

loss of trabeculation causing large, irregular marrow spaces *can be seen on radiograph - bone

Question 8

Agranulocytosis

Answer 8

WBC disorder, decrease in neutrophils. requires med consult.

Primary + Secondary (drug/chemical induced, ie. chemo)

Question 9

Cyclic Neutropenia

Answer 9

type of agranulocytosis -

cyclic decrease in circulating neutrophilic leukocytes.

Question 10

Leukemia

Answer 10

malignant neoplasms of blood.
abnormal WBC’s
sudden onset, deadly
oral: gingival enlargement, bleeding, petechiae, ecchymosis, NUG

Question 11

Ecchymosis

Answer 11

small, flat hemoragic patch

Question 12

Stages of Hemostasis

Answer 12

transient vasoconstriction
formation of platelet plug 
blood coagulation 
clot retraction
clot dissolution (fibrinolysis)

Question 13

Thrombocytopenia

Answer 13

platelet count less than 100k/mm

Question 14

Hemophilia

Answer 14

clotting defects
Type A - more common. deficiency of plasma
Type B- “Christmas disease”