Blood and Marrow

Question 1

Cytopenias are due to either ____ or _____.

Answer 1

increased destruction; decreased production

Question 2

Petechiae are indicative of ____.

Answer 2

thrombocytopenia

Question 3

____ are indicative of thrombocytopenia.

Answer 3

Petechiae

Question 4

What is the autoimmune destruction of platelets called?

Answer 4

Immune Thrombocytopenic Purpura (ITP)

Question 5

What is Immune Thrombocytopenic Purpura (ITP)?

Answer 5

the autoimmune destruction of platelets

Question 6

Name 2 alloimmune causes of thrombocytopenia.

Answer 6

1) post-transfusional thrombocytopenia

2) neonatal thrombocytopenia

Question 7

Name a drug that causes thrombocytopenia.

Answer 7

Quinidine

Question 8

What is quinidine?

Answer 8

an antiarrhythmic; causes thrombocytopenia

Question 9

Name 2 causes of non-immune/mechanical destruction of platelets.

Answer 9

1) disseminated intravascular coagulation (DIC)

2) mechanical heart valves/pumps

Question 10

What is DIC?

Answer 10

widespread activation of the clotting cascade