Blood and Immunity Pt2. Flashcards
Mneomic device for different WBC’s
Never (Neutrophils)Let(Lymphocytes) Monkeys (Monocytes) Eat (Esoinphils) Bannanas (Basophils)
What is the purpose of the Neutrophil? What stage does it show up in?
Act as the first responder - engulf and destroy pathogens. Second line of defence (innate)
What is a lymphocyte? What stage are the located in?
A subcategory of agranulocyte for B cells, T cells, and NK cells. Specific Immune response.
What is a monocyte? What stage is it a part of?
Differentiate into macrophages (WBC that eats intruders and displays broken down parts to help organize response), which are involved in antigen presentation and phagocytosis—inate and adaptive reactions.
What is an eosinophil?
Important for allergic reactions. Combat parasites.
What is a basophil?
WBC that releases histamines during allergic reactions and inflamation.
What is the first line of defense?
Physical: Skin, Mucus, Cillia, Acid stop pathogens.
What is the second line of defense?
Damaged cells release Histamines - which causes capillaries to become leaky. WBCs pass through the pores of capillaries and seek pathogens eating them by Phagocytosis. The main WBCs involved are granulocytes like Neutrophils. Monocytes become enlarged macrophages.
What is the third line of defense?
Specific: The body recognizes antigens on pathognes. Antibodies bind to antigens allowing granulocytes to ‘eat’ pathogens.
What are antibodies?
Y-shaped proteins that bind to antigens of pathogens - neutralizing them
What are the two lymphocytes?
T cells and B cell
What are antigens?
Proteins are used for identification on the surface of cells, like a fingerprint.
What is the antigen-antibody complex?
Antibodies link to antigens. Makes invaders easier to engulf.
What are the steps in the adaptive immune response?
- Helper t cells recognize foreign antigens and send out chemical messengers.
- Messengers cause B cells to clone themselves. Some form large plasma cells to make antibodies (factory) some form memory cells.
- Helper T cells active NK cells which puncture membranes of foreign cells (if the pathogen is a virus and infects the host cell the NK detects antigen change and kills it)
- Antibodies released by plasma cells bind to antigens and mark them for phagocytosis by macrophages.
- Once the battle is over suppressor T cells signal the immune system to shut down.
What is the point of memory B cells?
Hold info about shape of foreign antigen so we can produce antibodies quicker if invader comes back.
What antigen does type A blood have, what antibody in blood?
Antigen - A
Antibody - B
What antigen does type b blood have, what antibody in blood?
Antigen - B
Antibody - A
What antigen does type AB blood have, what antibody in blood?
Antigen - AB
Antibody - None