Blood Flashcards

1
Q

Why do we have blood?

A

Transport
Regulation
Protection

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2
Q

What does the blood transport?

A

Gases
Nutrients
Wastes

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3
Q

What does the blood regulate?

A

pH
Body temperature
Osmotic balance

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4
Q

What does the blood do to he protect the body?

A

Clotting

Immunity

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5
Q

What percent of blood is plasma?

A

55 percent

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6
Q

What percent of blood is formed elements?

A

45%

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7
Q

What is in formed elements?

A

White blood cells
Platelets
Red blood cells

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8
Q

What is the percentage breakdown of plasma?

A

91.5% water
7% plasma proteins
1.5% other solutes

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9
Q

In the plasma what are the plasma proteins?

A

54% Albumins
38% immunoglobuins
7% Fibrinogen

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10
Q

In the plasma what synthesise most of the proteins?

A

Hepatocytes

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11
Q

In the plasma what does the other solutes consist of?

A
Electrolytes
Nutrients
Gases
Regulatory substance
Waste products
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12
Q

What does the kidney/liver release when the blood has low oxygen levels? And why?

A

Erythopoietin (EPO)

To stimulate RBC production

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13
Q

What do proerythroblasts start to produce?

A

Hemoglobin

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14
Q

What escapes from the bone marrow into the blood?

A

Reticulocytes

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15
Q

How long does it take for the remaining organelles to become mature RBC?

A

1-2 days

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16
Q

How many RBC enter the blood stream per second?

A

2 million

17
Q

What is the only oxygen carrying protein in RBC?

A

Haemoglobin

18
Q

What is the shape of RBC and why?

A

Biconcave discs to increase surface area

19
Q

What is the structure and composition of RBC?

A

Strong, flexible plasma discs

No nucleus or other organelles

20
Q

What contains the haemoglobin?

A

Cytosol

21
Q

Why is blood red?

A

Haemoglobin is an iron rich pigment

22
Q

What does haemoglobin (Hb) do?

A

Binds to O2 in the capillaries surrounding the alveoli and ‘delivers’ the O2 to tissues down it’s concentration gradient.

23
Q

How many ‘haeme’ groups does each RBC have and what do the do?

A

Four that each combines with 1 O2 molecule.

24
Q

What shuttles O2 from the cell membrane to the mitochondria?

A

Myoglobin

25
Q

What is the iron containing protein in the skeletal and cardiac muscle?

A

Globular

26
Q

How many iron atoms does myoglobin (Mb) contain?

A

1

27
Q

What has a higher affinity for O2, Mb or Hb?

A

Mb

28
Q

Why is it important for Mb to have a higher affinity to O2 than Hb?

A

Enables O2 transfer at low partial pressure of O2

29
Q

When does anemia occur?

A

There is not enough blood

The blood doesn’t have enough haemoglobin

30
Q

How is anemia treated?

A

Transfusion

Taking in more iron

31
Q

Describe WBC and it’s role

A

Fight infections
Large in size
Have a nucleus

32
Q

Describe platelets

A

Smallest part of blood
No nucleus
Disk shaped ‘fragments’

33
Q

How long do platelets function?

A

10 days

34
Q

What is the function of platelets?

A

Involved in clotting of blood (adhesion, activation, aggregation)

35
Q

Where are the cells of the blood produced?

A

Bone marrow