Blood Flashcards

1
Q

Why do we have blood?

A

Transport
Regulation
Protection

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2
Q

What does the blood transport?

A

Gases
Nutrients
Wastes

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3
Q

What does the blood regulate?

A

pH
Body temperature
Osmotic balance

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4
Q

What does the blood do to he protect the body?

A

Clotting

Immunity

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5
Q

What percent of blood is plasma?

A

55 percent

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6
Q

What percent of blood is formed elements?

A

45%

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7
Q

What is in formed elements?

A

White blood cells
Platelets
Red blood cells

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8
Q

What is the percentage breakdown of plasma?

A

91.5% water
7% plasma proteins
1.5% other solutes

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9
Q

In the plasma what are the plasma proteins?

A

54% Albumins
38% immunoglobuins
7% Fibrinogen

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10
Q

In the plasma what synthesise most of the proteins?

A

Hepatocytes

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11
Q

In the plasma what does the other solutes consist of?

A
Electrolytes
Nutrients
Gases
Regulatory substance
Waste products
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12
Q

What does the kidney/liver release when the blood has low oxygen levels? And why?

A

Erythopoietin (EPO)

To stimulate RBC production

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13
Q

What do proerythroblasts start to produce?

A

Hemoglobin

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14
Q

What escapes from the bone marrow into the blood?

A

Reticulocytes

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15
Q

How long does it take for the remaining organelles to become mature RBC?

A

1-2 days

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16
Q

How many RBC enter the blood stream per second?

17
Q

What is the only oxygen carrying protein in RBC?

A

Haemoglobin

18
Q

What is the shape of RBC and why?

A

Biconcave discs to increase surface area

19
Q

What is the structure and composition of RBC?

A

Strong, flexible plasma discs

No nucleus or other organelles

20
Q

What contains the haemoglobin?

21
Q

Why is blood red?

A

Haemoglobin is an iron rich pigment

22
Q

What does haemoglobin (Hb) do?

A

Binds to O2 in the capillaries surrounding the alveoli and ‘delivers’ the O2 to tissues down it’s concentration gradient.

23
Q

How many ‘haeme’ groups does each RBC have and what do the do?

A

Four that each combines with 1 O2 molecule.

24
Q

What shuttles O2 from the cell membrane to the mitochondria?

25
What is the iron containing protein in the skeletal and cardiac muscle?
Globular
26
How many iron atoms does myoglobin (Mb) contain?
1
27
What has a higher affinity for O2, Mb or Hb?
Mb
28
Why is it important for Mb to have a higher affinity to O2 than Hb?
Enables O2 transfer at low partial pressure of O2
29
When does anemia occur?
There is not enough blood | The blood doesn't have enough haemoglobin
30
How is anemia treated?
Transfusion | Taking in more iron
31
Describe WBC and it's role
Fight infections Large in size Have a nucleus
32
Describe platelets
Smallest part of blood No nucleus Disk shaped 'fragments'
33
How long do platelets function?
10 days
34
What is the function of platelets?
Involved in clotting of blood (adhesion, activation, aggregation)
35
Where are the cells of the blood produced?
Bone marrow