block 5 lecture 11 spinal reflexes Flashcards

1
Q

what are the three main types of movement?

A

reflex, rhythmic and voluntary

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2
Q

what does the dorsal side of the spinal cord receive input from?

A

the senses

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3
Q

how do the sensory nerves enter the spinal cord?

A

dorsal roots

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4
Q

where does the spinal cord get bigger?

A

cervical and lumbar enlargements

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5
Q

where is the cervical enlargement?

A

C3-T1

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6
Q

where is the lumber enlargement?

A

L1-S1

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7
Q

how are the motor neurons in the grey matter of the spinal cord organised?

A

somatotopically - in relation to the body

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8
Q

what controls the axial parts of the body?

A

medial neurons

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9
Q

what do lateral neurons control?

A

distal parts of the body

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10
Q

what are alpha neurons part of?

A

final common pathway

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11
Q

where do upper motor neurons remain?

A

the central nervous system

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12
Q

what do lower motor neurons do?

A

send axons directly to muscles

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13
Q

what are the head muscles controlled by?

A

motor neurons in the brain stem

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14
Q

where are the muscles of the body motor neurons?

A

spinal cord

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15
Q

where are alpha neurons found in the spinal cord?

A

ventral horn

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16
Q

where do the alpha motor axons go?

A

the axons pass through the ventral root and through spinal nerve and terminate at neuromuscular juntsion

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17
Q

why are the ALPHA motor neurons?

A

thickest neurons meaning very rapid conduction

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18
Q

what is the main neurotransmitter in muscle control?

A

acetylecholine

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19
Q

what does acetylecholine do?

A

initiate muscle contraction

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20
Q

what does myelination allow?

A

saltatory conduction

21
Q

where is sensory input gathered from?

A

cerebral cortex, spinal interneurons, muscle spindle and skin

22
Q

what is the most common motor neuron disease?

A

ALS - amyotropic lateral sclerosis

23
Q

what happens in ALS?

A

progressive degeneration of the alpha motor neurons

24
Q

what are the symptoms of ALS?

A

muscle weakness, atrophy, difficulty breathing and swallowing and affect on cognitive function

25
Q

in ALS why are the eyes the last to be effected?

A

highly vasculated and highly innervated

26
Q

what is a possible cause of ALS?

A

too much glutamate in the brain

27
Q

what blocks glutamatergic neurotransmission?

A

riluzole

28
Q

does the sensory neurons always synapse with the interneurons in the reflex arc pathway?

A

may synapse directly with motor neuron

29
Q

where are muscle spindle in relation to normal muscle?

A

located parallel to muscle fibers

30
Q

what are normal muscle fibers called?

A

extrafusal muscle fibers

31
Q

what are the spindle muscle fibers called?

A

intrafusal

32
Q

how does the neuron carry information to the spinal cord?

A

1a afferent neuron wraps around the muscle spindle and goes into the dorsal root of the spinal cord

33
Q

what neuron innervate intrafusal muscle fibers?

A

gamma motor neurons

34
Q

what can muscle spindle detect?

A

changes on the muscle

35
Q

what is the stretch reflex?

A

myotactic reflex,

36
Q

what is the patella tendon tap?

A

this is a stretch reflex

37
Q

what happens when the tendon is tapped?

A

the quadriceps are stretched, 1a muscle spindle is activated, impulses travel to the spinal cord and activate motor neurons which release acetylecholine and contract the quads

38
Q

what is the stretch reflex reciprocal inhibition?

A

while stretch reflex is occurring, collateral branch send information to inhibitory interneruon to inhibit antagonistic muscle

39
Q

what does the mono synaptic stretch reflex control?

A

contracts agonist muscle

40
Q

what dose the reciprocal inhibition control?

A

inhibits antagonistic muscle

41
Q

in the inverse stretch reflex pathway what is the sensory organ?

A

golgi tendon

42
Q

where is the golgi tendon?

A

between tendon and muscle fibers, runs in series with the extrafusal fibers

43
Q

what happens in the inverse stretch reflex pathway?

A

it send out 1b afferent which synapses with interneruon in the spinal cord which inhibits the alpha motor neuron to stop muscle contracting

44
Q

what is the golgi tendon innervated by?

A

1b

45
Q

what is the threshold of the golgi tendon like?

A

very high - you need alot of contraction to activate

46
Q

what is the golgi tendon made up of?

A

collagen fibers

47
Q

how are the 1b activated?

A

force acts on the collagen fibers in the tendons to increase tension causing compression of the fibrils which activates dendrites of the 1b afferent

48
Q

what happens in the flexor withdrawl reflex?

A

nociceptors are activated, impulses are sent along afferent neurons………….