Block 4: CNS drugs and anaesthetics

Question 1

Something which prevents pain by causing loss of sensation is…

Answer 1

Anaesthesia

Question 2

When there is low serotonin and low noradrenaline activity the condition is…

Answer 2

Depression.

Question 3

When there is high dopamine activity the condition is…

Answer 3

Scizophrenia / psychoses.

Question 4

When there is low dopamine activity and high acetylcholine activity the condition is…

Answer 4

Parkinson’s disease.

Question 5

When there is high glutamate, low GABA and low serotonin activity the condition is…

Answer 5

Anxiety / insomnia.

Question 6

When there is high glutamate and low GABA activity the condition is…

Answer 6

Epilepsy.

Question 7

When there is low noradrenaline or high adrenaline the condition is…

Answer 7

Bipolar.

Question 8

Venlafaxine is a…

Answer 8

Serotonin and noradrenaline reuptake inhibitor (SNRI)

Question 9

Fluoxetine, citalopram, and sertraline are…

Answer 9

Selective serotonin reuptake inhibitors (SSRIs)

Question 10

Amitriptyline and nortriptyline are…

Answer 10

Tricyclic antidepressants (TCAs)

Question 11

Moclobemide is a…

Answer 11

Reversible monoamine oxidase inhibitor (RIMA)

Question 12

Tranylcypromine is a…

Answer 12

Monoamine oxidase inhibitor (MAOI)

Question 13

Chlorpromazine and pericyazine are…

Answer 13

Phenothiazines, typical anti-psychotics

Question 14

Haloperidol is a…

Answer 14

Butyrophenone, typical anti-psychotic.

Question 15

Clozapine, olanzapine, quetiapine, and risperidone are…

Answer 15

Atypical antipsychotics.

Question 16

Hallucinations, delusions, paranoia, disorganised speech, and disordered thinking are…

Answer 16

Positive symptoms of schizophrenia.

Question 17

Emotional and social withdrawal, lack of motivation, blunt effect, poverty of speech, poor judgement and insight are…

Answer 17

Negative symptoms of schizophrenia.

Question 18

Extrapyramidal effects, postural hypotension, anticholinergic, sedation, and weight gain are…

Answer 18

Adverse effects.

Question 19

Akathisia is…

Answer 19

Restlessness, fidgety. Extrapyramidal adverse effect.

Question 20

Dystonia is…

Answer 20

Muscle spasms, wry neck, torticollis. Extrapyramidal adverse effect.

Question 21

Oculogyric crisis is…

Answer 21

Upward rolling of eye balls. Extrapyramidal adverse effect.

Question 22

Parkinsonism is…

Answer 22

Fine tremors, bradykinesia, drooling, shuffling gait. Extrapyramidal adverse effect.

Question 23

Tardive dyskinesia is…

Answer 23

Irreversible, occurs with long term use, stereotyped involuntary movements. Extrapyramidal adverse effect.

Question 24

Lithium carbonate, carbamazepine, sodium valporate and lamotrigine are…

Answer 24

Mood stabilisers.

Question 25

A substance that diminishes the activity of an organ or tissue is a…

Answer 25

Sedative.

Question 26

Medications that induce sleep are…

Answer 26

Hypnotics (sleeping pills)

Question 27

Medications that prevent or treat anxiety are…

Answer 27

Anxiolytics.

Question 28

Propofol, thiopental sodium, isoflurane, sevoflurane, and nitrous oxide are…

Answer 28

General anaesthetics.

Question 29

Lidocaine, bupivacaine, and tetracaine are…

Answer 29

Local anaesthetics.

Question 30

—- depress the CNS, ease pain and cause loss of conciousness.

Answer 30

General anaesthetics.