Block 4: CNS drugs and anaesthetics Flashcards
Something which prevents pain by causing loss of sensation is…
Anaesthesia
When there is low serotonin and low noradrenaline activity the condition is…
Depression.
When there is high dopamine activity the condition is…
Scizophrenia / psychoses.
When there is low dopamine activity and high acetylcholine activity the condition is…
Parkinson’s disease.
When there is high glutamate, low GABA and low serotonin activity the condition is…
Anxiety / insomnia.
When there is high glutamate and low GABA activity the condition is…
Epilepsy.
When there is low noradrenaline or high adrenaline the condition is…
Bipolar.
Venlafaxine is a…
Serotonin and noradrenaline reuptake inhibitor (SNRI)
Fluoxetine, citalopram, and sertraline are…
Selective serotonin reuptake inhibitors (SSRIs)
Amitriptyline and nortriptyline are…
Tricyclic antidepressants (TCAs)
Moclobemide is a…
Reversible monoamine oxidase inhibitor (RIMA)
Tranylcypromine is a…
Monoamine oxidase inhibitor (MAOI)
Chlorpromazine and pericyazine are…
Phenothiazines, typical anti-psychotics
Haloperidol is a…
Butyrophenone, typical anti-psychotic.
Clozapine, olanzapine, quetiapine, and risperidone are…
Atypical antipsychotics.
Hallucinations, delusions, paranoia, disorganised speech, and disordered thinking are…
Positive symptoms of schizophrenia.
Emotional and social withdrawal, lack of motivation, blunt effect, poverty of speech, poor judgement and insight are…
Negative symptoms of schizophrenia.
Extrapyramidal effects, postural hypotension, anticholinergic, sedation, and weight gain are…
Adverse effects.
Akathisia is…
Restlessness, fidgety. Extrapyramidal adverse effect.
Dystonia is…
Muscle spasms, wry neck, torticollis. Extrapyramidal adverse effect.
Oculogyric crisis is…
Upward rolling of eye balls. Extrapyramidal adverse effect.
Parkinsonism is…
Fine tremors, bradykinesia, drooling, shuffling gait. Extrapyramidal adverse effect.
Tardive dyskinesia is…
Irreversible, occurs with long term use, stereotyped involuntary movements. Extrapyramidal adverse effect.
Lithium carbonate, carbamazepine, sodium valporate and lamotrigine are…
Mood stabilisers.
A substance that diminishes the activity of an organ or tissue is a…
Sedative.
Medications that induce sleep are…
Hypnotics (sleeping pills)
Medications that prevent or treat anxiety are…
Anxiolytics.
Propofol, thiopental sodium, isoflurane, sevoflurane, and nitrous oxide are…
General anaesthetics.
Lidocaine, bupivacaine, and tetracaine are…
Local anaesthetics.
—- depress the CNS, ease pain and cause loss of conciousness.
General anaesthetics.
