Block 2 Cartilage & Bone Flashcards
fundamental ct cell
fibroblasts
stuff secreted by ct
extracellular matrix
hydrated, amorphus material; looks smooth, homogeneous under the microscope; has no form; typically gel-like
ground substance
long unbranched polysaccharide of repeating disaccharide units one of which is an amino sugar; eg hyaluronic acid; can have up to 25,000 disaccharide units; very hydrophilic, combine with much H₂O
gags
composed of a linear protein core (produced in rough ER) to which a large number of glycosaminoglycans attach; thus they look like bristles on a brush or have christmas tree shape
PGs
fasten various components of the extracellular matrix to one another including collagen and transmembrane proteins of the cells synthesizing fibers
glycoproteins
three proteins of ground substance
gags, pgs, glycoproteins
fibers of extracellular matrix
collagen/elastic
blank types of collagen exist
15
chondrocytes are in cavities called blank
lacunae
cartilage has blank blood vessels
no
3 types of cartilage
hyaline, elastic, fibro
type 2 collagen
hyaline/elastic
type 1 collagen
fibrocartilage
types of growth of cartilage
appositional, interstitial
most common cartilage and is in nose, long bones, trachea, bronchi
hyaline
hyaline cartilage has a blank surface for joints and a high blank
smooth, high tensile strength
elastic cartilage is similar to hyaline cartilage but it has elastic fibers and includes a blank
perichondrium
external ear, epiglottis, external and internal auditory meatus has blank
elastic cartilage
elastic cartilage cells are blank than hyaline cells and has blank intercellular matrix
larger, less
fibrocartilage is blank due to large amounts of collagen
acidophilic
iv discs, tmj disc, menisci, pubic symphysis all have
fibrocartilage
matrix of bone is blank by calcium phosphate in the form of hydroxyapatite crystals
mineralized
bone has type blank collagen
1
osteocytes reside in blank
lacunae
bone formation steps
fibroblast, osteoprogenitor, osteoblast, osteocyte
osteoblasts becomes blank in its own secretion and turn into osteocytes
trapped
bone matrix that is not yet mineralized
osteoid
cluster of embryonic connective tissue cells (mesenchyme) secrete matrix →bone
intramembranous ossification
a hyaline cartilage model of the desired bone is first made and it is then stepwise replaced by cells secrete matrix →bone
endochondral ossification