Block 2 Flashcards
The following are true for non-trepanomal test in the detection of syphilis, except:
A. RPR test can serum to determine and evaluate neurosyphilis
B. Can have false positive result due to other infections
c.can be used to determine for evaluation of titers of antibodies
d. it can be used to monitor efficacy of therapy
RPR test can serum to determine and evaluate neurosyphilis
When visualized under darkfield microscopy, it is characterized as tightly coiled, thin, flexible spirochetes, with very fine spirals and one end is often bent, forming a hook.
Leptospira interrogans
Erythema migrans is the characteristics skin lesion of this disease.
Lyme Disease
True for the Treponomal test in the detection of syphilis.
a. It is persistently positive in Latent Syphilis
b. It detects the presence of treponomal antigen in the specimen
c. It utilizes cardiolipin as reagent
d. It detects the presence of anti-treponemal antibodies in the specimen
It detects the presence of anti-treponemal antibodies in the specimen
W/c of the ff is true for relapsing fever?
a. can be caused by borrelia burgdorferi (recurrentis)
b. Abrupt rise in the temperature after 1 week incubation
c. In the febrile phase, the organism is found in the spleen
d. antibodies appear during afebrile phase
Abrupt rise in the temperature after 1 week incubation
W/c of the ff statement is true?
a. Spirochetes do not contain peptidoglycan w/c defers from gram + bacteria
b. Leptospira and Borellia are the only known pathogens of family spirochetaceae
c. Borellia sp. belongs to the family spirochetaceae
d. The flagella is invested above the outer membrane
Borellia sp. belongs to the family spirochetaceae
W/c of the ff organism can be seen in the blood as a specimen w/ the use of aniline dyes?
Borrelia burgdorferi
A 24yr old man was wading in floodwater since yesterday up to today after heavy rain, he sought consultation at the SHH OPD. WHat prophylaxis should be given?
a. Doxycycline 100mg/cap, 2 capsule to be given daily w/in 72 hrs of exposure
b. Doxycycline 100mg.cap, 1 capsule to be given daily within 72 hrs of exposure
c. Doxycycline 200mg/cap, 1 capsule to be given daily w/in 72hrs of exposure
d. Doxycycline 100mg/cap, 2 caps to be given once a week until the end of exposure, 72 hrs within exposure
Doxycycline 100mg/cap, 2 caps to be given once a week until the end of exposure, 72 hrs within exposur
W/c of the ff is correctly paired according to the epidemiology of Lyme Disease?
a. Ixodes pacificus = Eastern US (West Coast)
b. Ixodes scapularis= Europe (damini)
c. Ixodes ricinus- West cost US (Europe)
d. Ixodes dammini=Northeast US (and Midwest)
Ixodes dammini=Northeast US (and Midwest)
A px from Connecticut, USA came in at the emergency room due to facial paralysis associated w/ painful radiculopathy. History showed he was a deer hunter & was treated & completed the oral antibiotic due to fever w/c happened 2 weeks ago. In this case, what antibiotic should be given? (B burgdorferi)
a. Doxycycline
b. Cetriazone (refractory cases)
c. Amoxicilin
d. Penicillin
(B burgdorferi)
Cetriazone (refractory cases)
W/c of the ff is true for the stages of syphilis?
a. Tertiary syphilis is high infectious
b. Primary syphilis is characterized by conylomata lata
c. Secondary syphilis is characterized by localized chancre and regional lymphadenopathy
d. Majority of latent syphilis will not progress to tertiary syphilis
Majority of latent syphilis will not progress to tertiary syphilis
W/c of the ff can be strained best w/ Silver impregnation technique for visualization of the organism?
a. Leptospira interogans
b. Borelia burgdorferi
c. Borelia recurrentis
d. Borelia vincentti
e. Treponema palilidum
Treponema palilidum
Sodoku is caused by spirochete:
a. Borelia buccalis
b. Spirilium minor (minus)
c. Borellia burgdorferi
d. Borelia refringes
Spirilium minor (minus)
Jarisch-Herxheimer reaction is characterized by the ff manifestations, except:
a. Purpura
b. Urticaria
c. Fever
d, Lymphadenopathy
Purpura
In Two-tiered test for lyme Disease, w/c test is used for Screening?
Enzyme immunoessay
The stage of Lyme Disease is characterized by arthalgia and neurologic manifestations.
Stage 2
A man came in w/ fever and neurologic deficit & seizure. HIstory revealed he has been wading in flood water 7 days prior. W/c statement is true to support your dx?
a. Doxycycline 100mg/tab, to be taken 1/day is the treatment modality
b. Agglutination test is the confirmatory test for such case
c. Urine is the specimen of choice for this case
c. There is good prognosis for this case
Agglutination test is the confirmatory test for such case
Liptospiroses
W/c of the ff sp is Louse-borne?
a. Borelia hermsii
b. Borelia vincenti
c. Borelia burgdoferi
d. Borelia recurrentis
Borelia recurrentis
Lyme disease is caused by these spirochete
a. Borelia burgdoferi
b. Borelia hermsii
c. Borelia recurrentis
Borelia burgdoferi
MATCH
- Bubo formation
- Groove sign
- Henderson
- Painless ulce
- Pseudobubo
Chancroid Lympogranuloma venereum Molluscum contagiosum Chancre Donovanosis
- Bubo formation- Chancroid
- Groove sign- Lympogranuloma venereum
- Henderson-Patterson bodies-Molluscum contagiosum
- Painless ulcer-Chancre
- Pseudobubo-Donovanosis
A woman complained of vaginal discharge ass w/ inguinal lymph node enlargement. McCoy cells culture of the cytobrush showed positive for inclusion bodies. What is the causative serovariant?
LGV 1
A determinant of the pathogenicity of Mycoplasma.
Adhesion factor
When the Chlamydias are stained w/ routine gram staining procedure, they will look like?
Gram-Negative Pleomorphic
True for Chlamydia, except:
a. Multiple intracellularly
b. the sp w/c infects human have common group antigens?
c. obligate intracellarly pathogens
d. Are gram negative bacteria
Multiple intracellularly
A 17yr old boy who works at cebu safari as caretaker of Moluccan, Major mitchell and Bared eye cocatoo. When he developed fever, chills and flu-like illness after 10 days. What is the drug of choice?
Doxycycline
W/c Chlamydial serotype is/are invlived in a px presenting w/ a painful inflammation & enlargement of the inguinal lymph nodes above the inguinal ligament?
a. L2
b. L3
c. D
d. L1
e. F
f. E
(LGV)
a. L2
b. L3
d. L1
A woman who had just gien birth had an onset of fever and body malaise after she got discharged from the hospital. Ultrasound showed tubo-ovarian abscess. The OBgyne specialist ordered culture of the abscess w/c showed a friend egg colony appearance. What is the causative organism?
Mycoplasma hominis
MATCH
- Gram negative intracellular bacteria
- donovan bodies-
- school of fish-
- clue cells-
- koilocytes-
N. gonorrheae Klebsiella granulomatis H. ducreyi Gardnerlla vaginalis HPV
- Gram negative intracellular bacteria- N. gonorrheae
- donovan bodies- Klebsiella granulomatis
- school of fish- H. ducreyi
- clue cells- Gardnerlla vaginalis
- koilocytes- HPV
W/c of the ff organism can spread through vertical route of transmission (Mother to fetus)?
a. C. trachomatis
b. M pneumoniae
c. Chlamydia psittaci
d. C. pneumoniae
C. trachomatis
W/c of the ff organism’s inclusion bodies will be stained dark with Iodine?
a. C. pneumoniae
b. C. psittaci
c. None
d. C trachomatis
C trachomatis
True for Mycoplasma organisms
a. Ability to grow in cell line culture media
b. can reproduce in cell media
c. resistant to penicillin and erythromycin
d. Obligate intracellular pathogens
can reproduce in cell media
T/F
Chlamydia infection is the most common sexually transmitted bacterial pathogen.
TRUE
T/F
To treat bacterial vaginosis among pregnant px, metronidazole administration is restricted to the 1st & 2nd trimester.
FALSE
A woman who had sexual contact w/ a man whom she met in a club a week ago is now complaining of vaginal discharge & dysuria. Gynecological findings showed cervical motion tenderness & non-foul smelling whitish discharge. The culture of the discharge in A8 agar showed growth w/ a change in the color of the medium after 2 days of incubation. What is the causative organism?
Ureaplasma urealyticum
A woman complained of vaginal discharge & dysuria, cytobrush culture on cell McCoy cell culture showed + for inclusion bodies. What is the serovariant?
C.t serovar E
The DNA & RNA content is equally distributed in EB. The reason why Elementary bodies are colored purple w/ Giemsa stain is?
a. The nucleiod has more DNA than the cytoplasm
b. The cytoplasm has more RNA than the nucleiod
c. The DNA is more concentrated in the nucleoid
d. The RNA is more concentrated in the nucleoid
The DNA is more concentrated in the nucleoid
A 6yr old child has lacrimation & mucopurelent discharge of the eye. The older sibling also got the same condition a few days ago. What is the causative agent?
C trachomatis serovar C
W/c of the ff antimicrobial is known to be the tx of choice for ehrlichae?
a. Fluoroquinolones
b. Trimethoprim-sulfamethoxazole
c. Penicillin G
d. Doxycycline
e. Chloramphenicol
Doxycycline
A mountaineer from Costa Rica, took a hoke through a forested & brushy area near his home. The next morning he noticed & removed a large insect from his tigh. About 7 days later, he experienced an abrupt onset of fever & malaise. He now seeks medical attention because he is concerned about a possible infection transmitted by the tick. W/c of the ff is known to the vector of the disease process?
a. Human body louse
b. Lone star tick
c. Chigger
d. Wood tick
e. Rat flea
(RMSF)
Wood tick
Rickketsial organisms are recovered in blood. What is the ideal time of collection for testing?
Convalescent period
All of the ff statements regarding R. akari are correct except:
I. It causes ricketsial pox
II. Ticks of the genus Amblyomma are responsible for transmission
III. The disease is mild
IV. Disease is more common in urban than in rural areas
Ticks of the genus Amblyomma are responsible for transmission
W/c of the ff bacteria is named after an investigator of typhus who was a victim of this disease?
a. Rickettsia akari
b. Ehrlichia ewingii
c. Rickettsia prowazekii
d. Erlichia chaffeensis
Rickettsia prowazekii