Biostats Flashcards

1
Q

What is the mean?

A

average

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2
Q

What is the median?

A

middle value

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3
Q

What is the mode?

A

most frequent value

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4
Q

What does sensitivity tell you?

A

people that have the disease with a positive test

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5
Q

What does specificity tell you?

A

people that don’t have the disease with a negative test

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6
Q

What does positive predictive value tell you?

A

probability of having a disease with a positive test

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7
Q

What does negative predictive value tell you?

A

probability of not having a disease with a positive test

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8
Q

What does incidence tell you?

A

new cases (rate per unit time)

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9
Q

What does prevalence tell you?

A

total cases (at one time)

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10
Q

What does the odds ratio tell you?

A

diseased are x times more likely to see risk factor

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11
Q

What does a confidence interval = 95% tell you?

A

95% sure it lies within the interval

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12
Q

What does relative risk tell you?

A

risk of getting a disease with known exposure

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13
Q

What is NNT?

A

number needed to treat to change 1 life

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14
Q

What does a p value < 0.5 tell you?

A

random chance that you will be wrong 1 time out of 20

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15
Q

What does a null hypothesis tell you?

A

nothing happened

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16
Q

What does power tell you?

A

probability of detecting a true intervention

17
Q

What is a type I error? (3)

A

P value error
false negative
“too optimistic”

18
Q

What is a type II error?

A

power error
false positive
“too pessimistic”

19
Q

What is accuracy? (2)

A

validity

“truth”

20
Q

What is precision? (2)

A

reliability

“keep making the same mistake”

21
Q

What are the phrases of clinical trials? (4)

A

Phase I - toxicity (“hurt pt?”)
Phase II - efficacy (“help pt?”)
Phase III - comparison (“any better?”)
Phase IV - post-marketing surveillance (“can they screw it up?”)

22
Q

What is a cohort study? (2)

A

prospective study that provides incidence (new cases)

uses relative risk

23
Q

What is a case control study? (2)

A

retrospective study that provides prevalence (total cases)

uses odds ratio

24
Q

What is a cross sectional study?

A

provides a prevalence “snapshot”

25
Q

What is a case report?

A

describes an unusual pt

26
Q

What is a case series report?

A

describes several unusual pts

27
Q

What are consensus panels?

A

panel of experts provide a recommendation

28
Q

What is clinical wisdom?

A

“I think…” paper

29
Q

What is a meta-analysis?

A

tries to combine data from many trials