Biopsy Flashcards
“bios” in biopsy means?
life
“opsy” in biopsy means?
look or appearance
It is the excision and examination of tissue from a living subject for diagnostic purposes.
Biopsy
In Berlin introduced surgical biopsy as an essential tool for diagnosis.
1870, Ruge and Joham Vert
Put forward an argument that confirmations should be made before surgeries for malignancies.
1889, Emarch
1st introduced this principle in US.
William Halsted
Study of exfoliated cells from a female genital tract by Papanicolaou.
1941
[9] Types of biopsy.
[EEI, ABC, PSW]
- Exfoliative cytology
- Excisional biopsy
- Incisional biopsy
- Aspiration/Needle biopsy
- Bite biopsy
- Cutaneous biopsy
- Punch biopsy
- Shave biopsy
- Wedge biopsy
Now widely used, especially for the diagnosis of malignant conditions and sites as the cervix, uterus, vagina, and the bronchial but also in urine and CSF and in fluid aspirated from the pleural and peritoneal cavities.
[types of biopsy]
Exfoliative biopsy
Smears made from suspected metastasis.
[types of biopsy]
Exfoliative cytology
Desquamated cells.
[types of biopsy]
Exfoliative biopsy
Sex hormonal status in females and Sex chromatin phenotype.
[types of biopsy]
Exfoliative cytology
Complete removal of lesion provides the MOST RELIABLE BIOPSY.
[types of biopsy]
Excisional biopsy
Permits the pathologist to examine all of the suspicious tissue.
[types of biopsy]
Excisional biopsy
Performed under local anesthesia before treatment is planned, but may be done using frozen section. (unfixed)
[types of biopsy]
Excisional biopsy
Cryostat- (-18 to -20C) (15-20 mins
[types of biopsy]
Excisional biopsy
Use of a needle and syringe to penetrate a lesion for aspiration of its contents.
[types of biopsy]
Aspiration/Needle biopsy
Cellular material expressed into slide and fixed with 95% ethanol.
[types of biopsy]
Aspiration/Needle biopsy
Small pieces are removed with special forceps.
[types of biopsy]
Bite biopsy
Example of bite biopsy.
[types of biopsy]
Endoscopic biopsy
Are removed from the skin lesion.
[types of biopsy]
Cutaneous biopsy
It is larger than 2 millimeter.
[types of biopsy]
Punch biopsy
Stained with H and E.
[types of biopsy]
Punch biopsy
Gross lesion assessment is very limited.
[types of biopsy]
Punch biopsy
Always present orientation problems and should be reserve for secretions requiring only histopathologic diagnostic.
[types of biopsy]
Shave biopsy
Curettage specimes
[types of biopsy]
Shave biopsy
Specimen is subdivided with a razor blade.
[types of biopsy]
Wedge biopsy
Size should be thicker than 3 to 4 mm.
[types of biopsy]
Wedge biopsy
If EM is used, it should be less than 1mm thin.
[types of biopsy]
Wedge biopsy
It refers to excisional or shell out and is a procedure in which the lesion is not entered but removed.
Marginal excision
Careful handling of the tissue is mandatory for?
Sarcoma
Immediate touch preparation for?
Lymphoma
Removal of part of a lesion for histological examination.
[types of biopsy]
Incisional biopsy
Preferred for large situated tumors that cannot be excised.
[types of biopsy]
Incisional biopsy
Removal of small piece of tumors.
[types of biopsy]
Incisional biopsy
Significant tumor remains.
[types of biopsy]
Incisional biopsy
