biomolecules Flashcards
polarity
distribution of charge within a molecule due to differences in electronegativity between atoms
functional groups
specific group of atoms that contribute to a predictable behavior of the molecule
most polar type of molecules
ones with charges like carbonic acid and NH3+
steroids
cholesterol derived non-polar hormones. consist of 4 hydrocarbon rings
amphipathic molecules
molecule with significant polar and nonpolar regions
ex: fatty acids
what kinds of solvents are physiologically toxic?
nonpolar solvents like hexane
what kind of compounds are lipophilic?
hydrocarbons (alkanes,alkenes, alkynes)
structure of an amino acid
an amino group, hydrogen, R group, and cooh group bound to a central carbon
what part of the amino acid determines its properties?
r group
r group classifications
positively charged, negatively charged, polar, nonpolar
which amino acid is achiral
glycine
which amino acids are aromatic
tyrosine, tryptophan, phenylalenine
which amino acids contain sulfur?
met and cyst
which amino acid breaks up secondary structure
proline (formation of proline kinks)
nonpolar amino acids
G, A,V, I, L, M, P, F, Y, W
polar amino acids
S, T, N, Q, C
positively charged amino acids?
R, K, H
negatively charged amino acids?
D, E
which amino acid is responsible for the formation of disulfide bridges in terciary protein structure?
cysteine- cystine
what bond joins amino acids to make proteins?
peptide bonds (dehydration)
- between cooh of previous amino acid and NH3 of next amino acid
direction of proteins
N terminus to C terminus
primary protein structure
sequence of amino acids, unchanged following denaturation
secondary protein structure
hydrogen bonding between the amine and cooh groups in the amino acid backbone that create alpha helicies and beta sheets
terciary structure
interactions between side chains, all proteins have this structure
quartenary protein structure
not all proteins possess this structure, interactions between multiple peptide subunits
lipids functions
storage, energy, structure, signalling
types of lipids
- fatty acids + derivatives
- cholesterol + derivatives
- eocosinoids (prostaglandins)
- terpenes and terpenoids
fatty acids
long chain carboxylic acids, can be branched or unbranched
TAGs
3 fatty acids bonded to a glycerol backbone. important for fat storage. bond can be broken via saponification