Biological basis of pratice Flashcards

1
Q

What is epigenetics?

A

Study of mechanisms by which gene expression is modified without changes in organisms genetic sequence.

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2
Q

Population genetics?

A

Studies about family/twins/adoption. It’s possible that mental health disorders are polygenic.

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3
Q

True or false: Genetics are a risk factor in developing some mental health disorders like schizophrenia or depression

A

True

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4
Q

What is a comparative approach?

A

Compares behaviours with other life forms.

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5
Q

What’s a developmental approach?

A

Studies the nervous system structure across different stages of development

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6
Q

What is chemoarchitectural approach?

A

Identification of differences in location of neurotransmitters/chemicals throughout the brain

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7
Q

What’s cytoarchitectural approach?

A

Identifies differences/variations in cell type, structure, and density throughout brain.

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8
Q

What’s a functional approach to neuroanatomy?

A

Identifies location of predominant control over various behavioural functions within brain

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9
Q

What is neuroplasticity?

A

Ability of brain to change its structure/function in response to pressures (internal and external). It compensates for loss in a specific area. Nerve signals may be rerouted, cells learn new function, and nerve tissues may be generated.

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10
Q

Left and right hemispheres of the cerebrum/function?

A

Left- involved in verbal language functions and memory
Right- involved in non verbal communication

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11
Q

What do the 4 lobes of the brain do?

A
  1. Frontal- personality, insight/judgement, problem solving
  2. Temporal- auditory, olfactory areas
  3. Optical- vision
  4. Parietal- taste, touch
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12
Q

What is limbic system in charge of?

A

Involved in some of the basic emotions and memory .

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13
Q

Basal ganglia function?

A

Motor function so its affected in parkinson’s disease.

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14
Q

What are neurotransmitters?

A

Small molecules directly/indirectly responsible for opening an closing ion channels

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15
Q

Neuromodulators?

A

Chemical messengers that make cell membranes more or less susceptible to effects of primary neurotransmitters

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16
Q

What are receptors?

A

Proteins for specific neurotransmitters. Sensitivity can change and develop a greater/lesser response to neurotransmitters.

17
Q

What does excitatory and inhibitory mean?

A

E- causes activity to occur
I- causes activity to decrease

18
Q

What are cholinergic receptors?

A

Primary neurotransmitter of parasympathetic NS. Excitatory and follow diffuse projections throughout the cerebral cortex/limbic system. 2 types are muscarinic and nicotinic

19
Q

Dopamine?

A

Excitatory neurotransmitter. Involved in cognition/motor/neuroendocrine functions. Simulates bodies feel good pathways. Will be increased in schizophrenia/decreased in parkinson’s.

20
Q

NE?

A

Excitatory. Involved in generating/maintaining mood states and sleep cycles. Dysfunction associated with anxiety and depressive disorders.

21
Q

What is epinephrine?

A

Similar to NE. Very small amounts of epinephrine are produced and release in the brain. There’s much higher concentrations in the rest of the body.

22
Q

What is serotonin?

A

Excitatory, involved in regulation of emotion/cognition/sensory perception/sleep/appetite. Also in food intake, hormone secretion, sexual behaviour, thermoregulation, and CV regulation. Associated with depression, insomnia, mania, OCD, panic disorders, and anxiety disorders.

23
Q

What is histamine?

A

Excitatory neurotransmitter that is associated with arousal/cognition/learning/memory/sleep/appetite/seizures. Many psych meds can block histamine causing side effects like sedation, weight gain, and hypoTN.

24
Q

What is GABA?

A

Inhibitory neurotransmitter that’s associated with seizure disorders and certain drug affinity

25
Q

What is glutamate?

A

Excitatory and may have role in learning/memory. May be associated with depression, anxiety, drug addiction, psychosis, parkinson’s disease.