Bacteriology 7: trueperella Flashcards
What species is trueperella common in?
Ruminant and pigs
What mechanisms does trueperella and Corynebacteria use to cause disease?
- Exotoxins: Pylosin and Phospholipase
- Pili and urease production
- Facultative intracellular
What disease is Urease production special to?
Corynebacteria- Pizzle rot
Are trueperella and Corynebacteria normal flora?
Yes
Where is trueperella?
- Mucus membranes
- Skin
Where is Corynebacterium pseudotuberculosis found?
Mucus membrane
GIT
Skin
Where is Corynebacteria
Renale found?
Genital tract of carrier cows and bulls
How to diagnose trueperella and Corynebacteria?
Signalment
Sample if in sterile site
Perform gram stain/diff quik
Culture for definitive diagnosis
*** Pathognomic usually so presumptive diagnosis is ok
What disease is caused by trueperella?
Trueperella pyogenes
-Abscesses
Trueperella pyogenes disease characteristics
- Most common cause of pyogenic DX in cattle
- May cause dx in other species: pigs, ruminants dogs
- Disease: Abscesses
- Cause: trauma
How to treat for trueperella and Corynebacteria
- Surgically debride and drain
ABX - Often not effective in chronic cases as bacteria are inside an abscess with thick capsules = poor penetration
- Ruminants may not be worth the cost of therapy
- Penicillin is drug of choice
What is the special characteristics of Corynebacterium pseudotuberculosis pathogenicity?
- Survive up to 8 mo in environment
- Found in lesions of infected animals which may acts as primary reservoirs
Diseases caused by Corynebacterium pseudotuberculosis?
- Caseous Lymphadenitis (CLA) “cheesy glands”
- Pigeon Breast/Pigeon Fever
DX of horses - Ulcerative lymphangitis
Caseous Lymphadenitis (CLA) “cheesy glands” Characteristics?
- Sheep and goat
- Major economically important DX
- Infection of superficial LN
- Can lead to Abscess in heart
- “Thin ewe syndrome” = generalized infection
Pigeon Breast/Pigeon Fever characteristics?
- DX of horses in Western USA
- Thick walled, external or internal(rare) abscesses
