Bacteria Flashcards

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1
Q

What are virulence factors?

A
  • molecules produced by bacteria, viruses, fungi and protoza

- addss to the effectivness

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2
Q

What are some general examples of virulence factors?

A
  • toxins
  • surface coats
  • surface receptors
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3
Q

How might s.aureus affect the skin?

A
  • rash
  • folliculitis
  • abscess
  • scaled skin syndrome
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4
Q

What are coagulase positive staph?

A
  • s.aureus
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5
Q

What are some coagulase negative staph?

A
  • s.epidermidis
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6
Q

What are some virulence factors associated with s.aureus?

A
  • finbrogen binding protein
  • protein A
  • TSST-1
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7
Q

TSST-1 is also called?

A
  • Toxic shock syndrome
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8
Q

What is the diagnostic criteria of TSST-1?

A
  • Fever > 39
  • diffuse malar rash
  • hypotension <90
  • > 3 organs involved
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9
Q

What is unquie to TSST-1 activity?

A
  • binds directly to the MHC-2 molecule

- massive release of cytokine and inappropriate immune response

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10
Q

What is necrotizing pneumonia?

A
  • severe complication of a quite mild infection

- destruction of immune cells

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11
Q

Streptococus pyrogens is a member of what group of strep?

A
  • Group A strep (GAS)

- B haemolyti

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12
Q

S. pyrogens is associated with what skin infections?

A
  • impetigo
  • cellulitis
  • necrotizing fasciitis
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13
Q

Alpha haemolysis looks like what on the agar plate, and what causes it?

A
  • partial haemolysis

- s.viridans

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14
Q

Beta haemolysis looks like what on the agar plate and what causes it?

A
  • complete haemolysis
  • s.pyrogens
  • GAS
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15
Q

Gamma haemolysis looks like what on agar plate and what causes it?

A
  • no haemolysis

- eneterococcus

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16
Q

What virulence factors are associated with s.pyrogens?

A
  • protein M

- fibronectin-binding proteins

17
Q

Protein M virulence factor associated with____?

A
  • s.pyrogens
18
Q

Protein A virulence factor associated with_____?

A
  • s.aureus
19
Q

Toxic shock is associated with what bacteria?

A
  • s.aureus
20
Q

What is a carbuncle?

A
  • red, swollen, painful cluster of boils connected to each other under the skin
21
Q

Gram positive bacteria stains what colour?

A
  • purple
22
Q

What must you consider before prescribing antibiotics?

A
  • Is the bacteria cultrued commensal?
23
Q

What treatment could be given in an MRSA infection?

A
  • doxycycline

or ( vancomycin, co-trimoxazole)

24
Q

What organism causes a scabies infection?

A
  • sarcoptes scabiei
25
Q

What is the incubation time in scabies?

A
  • 6 weeks

- highly infectious

26
Q

What treatment can be given to scabies?

A
  • malathion lotion

- benzyl Benzoate (avoid in kids)

27
Q

What virus causes shingels?

A
  • Varicella Zoster virus
28
Q

Erythematous starting on the trunk may be due to what?

A
  • Roseola

- Scarlet fever

29
Q

What virus causes chicken pox

A
  • Varicella Zoster virus