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BMB Test 4 > B7-080 Substance Use Disorder > Flashcards

B7-080 Substance Use Disorder Flashcards

1
Q

diagnosis of substance use disorder requires symptoms in what general categories [4]

A

impaired control
physical dependence
social problems
risky use of substance

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2
Q

[…] symptom of substance use disorder indicates the individual is at risk

A

one

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3
Q

[…] symptoms indicate mild substance use disorder

A

2-3

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4
Q

[…] symptoms indicate moderate substance use disorder

A

4-5

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5
Q

[…] symptoms indicate severe substance use disorder

A

6+

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6
Q

therapy based upon principles of operant conditioning

A

contingency management

(often CM is added to another SUD treatment)

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7
Q

community reinforcement approach plus vouchers is an example of what type of therapy?

A

contingency management

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8
Q

the matrix model is helpful for individuals with […] SUD

A

stimulants

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9
Q

the matrix model is an example of […] therapy

A

behavioral

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10
Q

12 step facilitation therapy is an example of […] therapy

A

behavioral

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11
Q

Medication Assisted Treatment (MAT) is used for […] use disorder

A

opioid

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12
Q

OUD medications [3]

A

methadone
buprenorphine
naltrexone

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13
Q

OUD medication that is a full mu receptor agonist

A

methadone

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14
Q

OUD medication that is partial mu receptor agonist

A

buprenorphine

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15
Q

OUD medication that is mu receptor antagonist

A

naltrexone

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16
Q

has a very high affinity for mu receptors, so can out-compete other substances for binding

limits possibility of overdose [2]

A

buprenorphine
naltrexone

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17
Q

precautions of methadone [2]

A

prolonged QT
fatal overdose

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18
Q

common side effects of methadone [3]

A

sweating
constipation
respiratory depression

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19
Q

therapeutic dosage of methadone in adults

A

80-120 mg

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20
Q

precautions of buprenorphine [2]

A

withdrawal symptoms if taken too soon after an opioid
hepatitis

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21
Q

common side effects of buprenorphine [3]

A

nausea/vomiting
dizziness
constipation

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22
Q

can be administered via sublingually, orally, subq, subdermal implant, or transdermal patch

A

buprenorphine

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23
Q

common side effects of naltrexone [4]

A

nausea/vomiting
somnolence
injection side reaction
elevated liver enzymes

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24
Q

the patient must be opioid free for […] prior to using injectable naltrexone

A

7-10 days

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25
Q

precautions to naltrexone [2]

A

withdrawal if currently taking opioids
routine liver function monitoring

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26
Q

available orally or in IM monthly injections

A

naltrexone

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27
Q

depot injections are generally preferred for long term treatment, but what is a consideration?

A

naltrexone/buprenorphine cause withdrawal symptoms when taken concurrently with opioids

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28
Q

why do patients who were incarcerated have an increased risk of overdose after leaving the detention center?

A

naltrexone causes resensitization of mu receptors, so their previous usual dose is much more dangerous

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29
Q

rescue medication to prevent opioid overdose

A

naloxone

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30
Q

physicians must complete training to waiver to prescribe and dispence

A

buprenorphine

(under the Drug Addiction Treatment Act)

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31
Q

therapy that helps patients develop critical skills that support long-term abstinence such as recognizing and avoid the situation in which they are most likely to use

A

CBT

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32
Q

therapy that uses a prize-based system that rewards patients who abstain

A

contingency management therapy

33
Q

addresses the impact of drug use patterns on familial relationships and improves overall family functioning

A

family therapy

34
Q

therapy that addresses patient readiness for change and helps resolve ambivalence toward drug treatment/use

A

motivational enhancement therapy

35
Q

a breakdown of intention to limit consumption in a particular situation

A

impaired control

36
Q

biological adaptation to persistent drugs in the body

A

physical dependence

37
Q

drug use in particularly hazardous settings

A

risky use

38
Q

role failures impacting family and societal functioning

A

social problems

39
Q

adaptive changes in the […] as a result of repeated intoxication/withdrawal cycles lead to reward deficit syndrome, increased stress reactivity and emotional dysregulation

A

amygdala

40
Q

the […] part of the brain is involved in drug reward

A

nucleus accumbens

41
Q

modes of administration that maximize […] are most reinforcing

A

rate of onset

IV> smoked > snorted > orally injested

42
Q

Substance is taken in larger amounts or over a longer period than was intended

is a symptom of

A

impaired control

43
Q

tolerance or withdrawal are symptoms of

A

physical dependence

44
Q

There is a persistent desire or unsuccessful efforts to cut down or control substance use

is a symptom of…

A

impaired control

45
Q

A great deal of time is spent in activities necessary to obtain, use or recover from the effects of a substance

is a symptom of…

A

impaired control

46
Q

craving or a strong desire or urge to use the substance

is a symptom of…

A

impaired control

47
Q

Recurrent substance use resulting in a failure to fulfill major role obligations at work, school or home

is a symptom of…

A

social problems

48
Q

Continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance

is a symptom of…

A

social problems

49
Q

Important social, occupational, or recreational activities are given up or reduced because of substance use

is a symptom of…

A

social problems

50
Q

Recurrent substance use in situations in which it is physically hazardous

is a symptom of…

A

risky use`

51
Q

Substance use is continued despite knowledge of persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by the substance

is a symptom of…

A

risky use

52
Q

The partial agoinist character of buprenorphine can elicit […] symptoms

A

withdrawal

53
Q

the most successful approach to increase adherance to treatment and reduce illicit opioid use

A

Opioid agonists combined with psychosocial treatments

54
Q

Individuals initiating OUD treatment with either [….] had better clinical and cost outcomes in several areas than those beginning their OUD treatment via an alternative care pathway

A

buprenorphine or methadone

55
Q

The core principles of […] programs are acceptance, surrender and participation in the activities through peer-based meetings

A

12 step

56
Q

therapy that centers around identifying triggers and avoiding risky situations

A

CBT

57
Q

an incentive-based program based on operant principles

A

contingency management therapy

58
Q

therapy that addresses ambivalence about recovery

A

motivational therapy

59
Q

must be administered at certified Addiction Treatment Centers

A

methadone

60
Q

requires specialized training to initiate therapy and avoid precipitated withdrawal

A

buprenorphine

61
Q

The symptoms of preoccupation and anticipation of drug use reflect adaptive changes in which brain regions?

A

anterior cingulate, prefrontal cortex

62
Q

brain structures guiding incentive salience

A

nucleus accumbens and thalamic nucleus

63
Q

therapy particularly beneficial to address behavioral issues with young people and re-direct risky behaviors

A

family therapy

64
Q

reverses monoamine and vesicular transporters leading to greater dopamine efflux

A

methamphetamine

65
Q

factor that most predicts increased severity and poor clinical course of SUD

A

early use

66
Q

increases the risk of developing SUDs by 2 to 4 times but it is not a predetermined outcome

A

family history

(Children of parents with SUD are still more likely NOT to develop an SUD than to develop one)

67
Q

accounts for about 60% of the risk for developing SUD but does not predict the severity or course of illness

A

genetics

68
Q

explores the positive and negative consequences of continued drug use and incorporates self-monitoring techniques to identifiy situations that increase risk for use and helps develop strategies to cope with cravings and avoid high-risk situations

A

CBT

69
Q

therapy that specifically addresses cue-induced relapse

A

CBT

70
Q

commonly incorporated into the film with buprenorphine to prevent melting/injecting drug

A

naloxone

(due to poor oral availability)

71
Q

naloxone has […] oral availability

A

poor

72
Q

naltrexone has […] oral availability

A

good

73
Q

withdrawal symptoms are the result of

A

physiological dependence

74
Q

reduces cravings and prevents withdrawal, but with a limited ceiling of effects thereby reducing the risk of fatal overdose

A

buprenorphine

75
Q

methadone has […] potential for fatal overdose

A

full

76
Q

buprenorphine has […] potential for fatal overdose

A

limited

77
Q

what factor limits the use of buprenorphine?

A

severe physical dependence

78
Q

integrated treatment plan incorporating pain management with motivational counseling to encourage adherence to treatment and monitoring

A

matrix model

79
Q

patients with long history of SUD abuse have likely failed other therapies, so […] is used

A

matrix model

BMB Test 4 (14 decks)

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