B7-0016 Spinal Cord and Long Pathways Flashcards
group of neuronal cell bodies outside CNS
ganglion
group of neuronal cell bodies inside CNS
nucleus
bundle of axons in CNS
tract
send an axon to synapse on neurons in another structure
project to
synapse in/on
terminate
cross from one side of the brain to another
decussate
(ipsilateral or contralateral)
contributes to regional specialization
somatotopy
motor neuron pools reside in the […] laminae
ventral
dorsal laminae primarily receive […] information
sensory
label the tracts
voluntary motor pathway
corticospinal tract
upper motor neuron of the corticospinal tract
cortical motoneuron
lower motor neuron of the corticospinal tract
alpha motoneuron
where does the corticospinal tract dessucate?
caudal end of medulla (pyramidal decussation)
flaccid paralysis indicates […] motor neuron damage in the corticospinal tract
lower
spastic paralysis indicates […] motor neuron damage in the corticospinal tract
upper
a lesion rostral to the decussation will cause deficits […] to the lesion
contralateral
a lesion caudal to the decussation will cause deficits […] to the lesion
ipsilateral
the corticospinal tract begins at the […], descends ipsilateral and decussates at the […], then descends contralaterally
motor cortex
pyramidal decussation
1st synapse of the corticospinal tract
anterior horn (spinal cord)
1st order neuron of the corticospinal tract
UMN (motor cortex)
2nd order neuron of the corticospinal tract
LMN (leaves spinal cord)
2nd synapse of corticospinal tract
NMJ at skeletal muscle
tract that senses pressure, vibration, fine touch, proprioception
dorsal column
1st synapse of the dorsal column
nucleus gracilis (legs)
nucleus cuneatus (arms)
in ipsilateral medulla
2nd synapse of the dorsal column
VPL in thalamus
the 3rd order neuron of the dorsal column projects to
primary somatosensory cortex
tract that senses pain, temperature
spinothalamic
1st synapse of the spinothalamic tract
posterior horn (spinal cord)
2nd synapse of the spinothalamic tract
VPL (thalamus)
the 3rd order neuron of the spinothalamic tract projects to
primary somatosensory cortex
where does the dorsal column decussate?
in the medulla, then second order neuron ascends contralaterally as the medial lemniscus
where does the spinothalamic tract decussate?
in spinal cord as the anterior white commisure
composed of large-diameter, myelinated fibers that are rapidly conducting
DC/ML
composed of small diameter myelinated and unmyelinated fibers
slowly conducting
spinothalamic
1st order neuron of the dorsal column
sensory nerve ending in dorsal root ganglion
enters spinal cord, ascends ipsilaterally
1st order neuron of spinothalamic tract
sensory nerve ending composed of A-delta and C fibers in the dorsal root ganglion.–> enters spinal cord
deficits to the spinothalamic tract in the spinal cord will involve […] body surface […] the level of the lesion
contralateral
below
the components of the sympathetic nervous system reside in the […] cord
thoracic
(injury below T10ish should not damage sympathetic pathway)
postcentral gyrus contains […] information
sensory
primary somatosensory cortex
sensory pathways are [afferent/efferent]
afferent
(toward CNS)
fibers in the dorsal column carry […] information
sensory
loss of touch and proprioception indicates damage to which pathway
DC/ML
damage to the medial lemniscus would result in
sensory loss from the neck down
(contains sensory axons from all levels of the spinal cord)
the […] cord has the most white and gray matter
cervical
the […] cord has the least white and gray matter
sacral
the […] cord is characterized by weenie dorsal and ventral horns
thoracic cord
the […] cord has less white matter than cervical with equally large dorsal and ventral horns
lumbar
when, on a given part of the body, sensation is lost for one modality and retained for the other
dissociated loss
loss of touch/vibration, but retention of pain and temperature is an example of
dissociated loss
loss of DC/ML pathway, retention of spinothalamic
damage to the cortex constitutes an […] motor neuron lesion
upper
ventrolateral white matter contains axons in which pathway
spinothalamic
carry pain and temperature information from the contralateral body surface
spinothalamic
information in the pain pathway decussates in the […] so white matter axons in the cord represent the […] side
spinal cord
contralateral
(spinothalamic tract)
because the spinothalamic is an ascending tract, the loss will occur
regions below the level of deficit
how are dorsal columns organized?
arms outside (lateral)
legs inside (medial)
how are the corticospinal and spinothalamic tracts organized?
legs lateral
arms medial
descending tract
corticospinal
ascending tracts
dosal column
spinothalamic
controls voluntary motor movements
corticospinal
senses pressure, vibration, fine touch
dorsal column
senses pressure, vibration, fine touch in lower extremity
fasciculus gracilius of DC/ML (medial)
senses pressure, vibration, fine touch in upper extremity
fasciculus cuneatus of DC/ML (lateral)
senses crude touch and pressure
anterior spinothalamic tract
senses pain, temperature
lateral spinothalamic tract
[…] and […] synapse, then cross
spinothalamic and dorsal column
[…] crosses, then synapses
corticospinal tract