Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

IBI Test 3 > B3.045 - Blood and Tissue Parasites > Flashcards

B3.045 - Blood and Tissue Parasites Flashcards

1
Q

what bug transmits leishmania

A

sand fly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

free living amebae we should know

A

naegleria fowleri

acanthamoeba sp

balamuthia mandrillaris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

when treating non falciparum malaria what do you always add if not contraindicated

A

primaquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which drug has high resistance

A

chloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

free living amebae found where

A

EVERYWHERE!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is your typical classic patient presenting with Chagas

A

South american patient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dx of toxoplasma gondii

A

imagin

serology

histo - free tachyzoites and tissue cysts

PCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

rapid antigen tests must be backed up by what

A

thick smear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how is babesia transmitted

A

via Ixodes tick

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

when do you get draws for malaria blood smear

A

3 spaced 12-24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

treatment of babesia

A

Atovoquone + azithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

pathogenesis of babesia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

where is the epimastagote of trypanosoma sp found

A

the vector

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the most dangerous time for malaria age wise

A

late infancy through childhood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is this (its from the eye)

A

amebic keratitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

which type of malaria causes continuous fever

A

falciparum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Clinically important species of trypanosoma

A

T. brucei gambiense

T. brucei Rhodesiense

T. Cruzi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

diagnostic options of T. brucei

A

Labs - anemia, leukocytoiss, thrombocytopenia, hypergammaglobulinemia

tripomastigotes in blood

History

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

how is T. brucei transmitted

A

tsetse fly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

malaria treatment flow chart

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

malarial paroxysm (3 stages)

A
  1. cold or chilling stage
  2. Hot stage
  3. sweating stage
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Leishemania hemoflagellates live where

A

intracellularly in MACROPHAGE!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

treatment of leishmania

A

expert consultation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

how is cutaneous leishmaniasis treated

A

usually treats itself you can just help with scar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What is this

A

T. Brucei gambiense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

what transmits T. cruzi

A

triatome bugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What is the causative agent of malaria

A

plasmodium Flalciparum and vivax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

how is malaria transmitted

A

anopheles mosquito

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

where is the trypomastigote found in trypanosoma sp and what are some of its features

A

non dividing, motile, found in blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

what are the 5 species of plasmodium to know

A

falciparum vivax ovale malariae knowlesi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

hallmark of malaria and which types

A

Cyclic fevers

Every 48 hours w vivax and ovale

Every 72 hours malariae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

diagnosis fo malaria

A

identification of parasite in blood on blood smear via Giemsa stain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

what is this

A

Chancre at site of T. Brucei bite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

T. cruzi who gets it

A

all acute or reactivated

Congenital

Chronic in kids and adults up to 50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

why is blood transfusion no longer recommended

A

lack or correlative outcome data

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q
A

Babesis

Note: maltese crosses and more extracellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

where do you look up malaria treatments

A

CDC yellow book

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

clinical symptoms of free living amebea

A

CNS disease

PAM - infection by swimming, diving, netti pot

GAE - enters through skin (injury), lung, muchosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

if your patient has severe malaria what do you do

A

quinidine if avail, if not call CDC malaria hotline

40
Q

clinical symptoms of toxoplasma gondii in immunocompetent host

A

asymptomatic

flu like symptoms - monospot-negative but looks like mono

41
Q

how is T. cruzi transmitted

A

kissing bug

Reduviid bug

Triatome bug

Transfusions

42
Q

how does PAM present and what organism is it associated with

A

rapid onset, headache, looks like bact. meningitis, death usually within a week

maegleria fowleri

43
Q

specific diagnosis of babesia

A

peripheral blood smear, look fro ring forms and maltese crosses

44
Q
A

Ramonas signs

indicates T. Cruzi

45
Q

what parasite lives in humans macrophages

A

leishmania sp

46
Q

serology of babesia

A

B. microti IFA

47
Q
A

toxoplasma gondii

48
Q

what causes the african sleeping sickness

A

T. brucei

49
Q

Dx of PAM

GAE

AK

A

PAM - microscopic exam of CSF

GAE - histo - brain, skin

AK - culture, micro, histo

50
Q

GAE symptoms and what orgnanism is it associated with

A

hematogenous dissemination to brain, fever

acanthamoeba

51
Q

toxoplasma gondii definitive host

A

cats

52
Q

what are these examples of and where are they found

A

mucocutaneous leishmaniasis

new world, brazil, amazon

53
Q

describe the complications that come from each type of malaria

A
54
Q

Why are only the ring forms seen on this smear and what type is it

A

Thin, bc the larger ones are sequestered in organ system

55
Q

what does primaquine do

A

schizonticidal

56
Q

symptoms of T. cruzi

A

mostly in <15 yo

local reaction chagoma followed by malaise, fever, ROMANAS SIGN!

Painless unilateral edema of both eyelids

57
Q

amebic keratitis

how do you get it, what is the organism, who gets it

A

infection of cornea ass with contact wearers

keratitis

immunocompetent adults

acanthamoeba sp

58
Q

what is sequestration

A

endothelial margination and stickiness

due to erythrocytes containing mature forms sequester in postcapillary venules of organs

59
Q

LIfe cycle of malaria

A
60
Q

what does babesia look and act like

A

Looks like malaria, acts like Lyme disease

61
Q

blood smear is done on what for malaria

A

thin and thick blood films, EDTA blood

Thick - screening (sn)
Thin - sp identification

62
Q

what is a lab criteria to keep an eye on in malaria

A

parasitemia >3%

63
Q
A

T. cruzi

64
Q

clinicla syndromes of leishmaniasis

A
65
Q

babesia is often seen as what

A

coinfection wiht other diseases transmitted by ixodes

66
Q

incubation time of malaria

A

2-3wk range

67
Q

taoxoplasma gondii clinical symptoms in immunocompromised host

A

febrile illness wiht CNS symptoms, can be primary infection or reactivation

68
Q

highest risk of getting malaria

A

visiting friends and relatives

69
Q

most virulent species that causes malaria

A

falciparum

70
Q

Clincal symptoms of malaria

A
71
Q

what is this

A

Thick smear, look for pink center and blue/purplish ring

72
Q

what is a fast test for malaria

A

Antigen detection rapid test but decreases sesnsitivity for non falciparum sp

73
Q

clinical disease of T. cruzi characterized by

A

Mega Heart - cardiomyopathy, arrythmia

Mega colon - loss of peristalsis

Mega esophagus - loss of peristalsis

74
Q

what causes malarial symptoms

A

killing red blood cells

Cytokine release TNF –> fever

75
Q

Descrieb the trypanosoma life cycle

A
76
Q

which parasite is free living

A

amebae

77
Q

what is african sleeping sickness signs stage 1

A

winter bottom sign - posterior cervical adenopathy

chancre at bite site

78
Q

Where is leishmania found in the world (blue parts of map)

A

think brazil

79
Q

seasonality of babesia

A

June-august

80
Q

trypanosoma cruzi life cycle

A

Think: Contaminative transmission

81
Q

malaria immunity requires what

A

repeated exposure

wanes with lack of exposure

82
Q

diagnosis of leishmania sp

A

clincal/epidemiological

spleen, liver, bone marrow aspirate

usually a bone marrow aspirate

83
Q

labs of babesia species

A

decreased platelets, Hb, WBC

84
Q

What causes chagas disease

A

T. Cruzi

85
Q

diagnosis of T. cruzi

A

blood smears acutely

Histo chroncally

86
Q

epidemiology of T. cruzi

A
87
Q

where is teh amastigote of trypanosoma sp found and describe its features

A

Intracellular

dividing, found in tissues, nonmotile

88
Q

which drugs are tissue schizonticidal and blood shizonticidal

A
89
Q

toxoplasma gondii clincial symptoms congenital

A

classic triad
1. chorioretinitis

  1. intracranial calcifications
  2. hyrdocephalus
90
Q

what are stage 2 symptoms of T.brucei caused african sleeping sickness

A

wasting, meningoencephalitis

CNS issues

altered sleeping cycle

91
Q

toxoplasma gondii lifecycle

A
92
Q

what are these examples of

A

cutaneous leishmaniasis

93
Q

what are these examples of

A
94
Q

Sporizoites penetrate the hepatocyte via what adn then what happens

A

attachment of the sporozoite surface protein coat to the hepatocyte haparan sulfate glycoproteins and LDL receptor

95
Q

how do you differentiate T. cruzi from T. brucelis

A

the kitenoblasts are larger on Cruzi

96
Q

smyptoms of malaria

A

fever, chills, headache

97
Q

what are clinical symptoms of babesia

A

febrile illness with anemie

worse in asplenic

shaking, chills, sweats, fever, headache, myalgias

IBI Test 3 (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions