B3.038 - Hematopoeisis Flashcards
1
Q
What acts on pluripotent stem cells?
A
SCF, IL-6, Flt3L
2
Q
What acts on lymphoid stem cells
A
SCF, Ftl3L, IL-7
3
Q
What acts on trilineage myeloid stem cells
A
IL-3, IL-6, GM-CSF
4
Q
What is extra medullary hematopoeisis
A
Reactivation of hematopoeisis outside bone marrow due to insufficient bone marrow reserve
5
Q
What are sites of extramedullary hematopoeisis
A
Lymph, liver, spleen, soft tissue
6
Q
What are neutrophils
A
Phagocytes, segmented nucleus
7
Q
What are examples of primary granules
A
Myeloperoxidase Lysozyme Defensins Acid hydrolases Neutral Proteases
8
Q
What are examples of secondary granules in cytoplasm of neutrophils
A
Lysozyme Collagenase Lactoferrin Plasminogen activator Histamine Alkaline phostphatase