AUTONOMIC NERVOUS SYSTEM Flashcards
ANS
-ANS usually operates without conscious control
-hypothalamus and brainstem regulate ANS reflexes
Interceptors
-sensory receptors in blood vessels, organs, muscles and the nervous system monitors conditions in the internal environment
Dual innervation
-organs receive both sympathetic and parasympathetic impulses
-usually antagonists
Sympathetic division
-exercise, excitement and emergency
-functions to prepare the body for physical activity or a stressful situation
Thoracolumbar division
Parasympathetic division
-helps the body relax and perform vital functions
-conserves energy and replenishes stores
-maintains homeostasis at rest
-“rest and digest”
Craniosacral division
Ganglia
-clusters of cell bodies that result in an enlarged portion
-found in PNS
-called nuclei in the CNS
In sympathetic = sympathetic trunk ganglia and prevertebral ganglia
Sympathetic trunk ganglion:
-along either side of the spinal cord
-innervate organs above the diaphragm
Prevertebral ganglia:
-anterior to the spinal cord
-innervate below the diaphragm
-celiac, mesenteric ganglions
In parasympathetic = terminal ganglia
-located near target organs or within the wall of effector
-parasympathetic preganglionic neurons are long, postganglionic neurons are short
Preganglionic neurons
-postganglionic neuron in unmyelinated
-can excite or inhibit effectors
-can release wither acetylcholine or norepinephrine
Postganglionic neurons
Parasympathetic division:
-presynaptic neurons synapse with 4 or 5 post-synaptic neurons which supply a single visceral layer
Sympathetic division:
-terminate in several different visceral effectors
-response is widespread
-preganglionic neurons are highly branched
-may synapse with > 20 post-synaptic neurons
Neurotransmitters
-Acetylcholine
-Norepinephrine
Acetylcholine – detected by cholinergic receptors
-at all ganglia
-used in all of the synapse of the sympathetic and parasympathetic ganglia
-cholinergic receptors
-two subtypes:
1.Nicotine:
-found in ganglia
-Ach binding is always
excitatory
2.Muscarinic:
-found in synapses with the
effector organs in the
parasympathetic NS
-at all effectors in
parasympathetic and some
in sympathetic
-usually excitatory
sometimes inhibitory
Norepinephrine – detected by adrenergic receptors
-at some effectors in sympathetic except sweat glands (Ach)
-androgenic
-excitatory or inhibitory
Agonists
-substances that bind and activate a receptor
-ex. nicotine or muscarine
Antagonist
-substances that bind and block a receptor
-ex. atrophine (blocks muscarine ACH receptors)