Autonomic and Endocrine Systems Flashcards

1
Q

What are the Two Classifications of Motor(Efferent) Neurons?

A

Somatic and Autonomic Motor Neurons

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2
Q

Are Somatic Motor Neruons under Voluntary or Involuntary Control?

A

Voluntary

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3
Q

What do Somatic Motor Neurons Innervate?

A

Skeletal Muscles under cerebrocortical control

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4
Q

What are the Two Classifications of Autonomic Motor Neurons?

A

Sympathetic and Parasympathetic

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5
Q

Are Autonomic Motor Neurons under Voluntary or Involuntary control?

A

Involuntary

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6
Q

Where does the Autonomic System recieve its Sensory Input from?

A

Mainly Interoceptors (Internal sensing)

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7
Q

The Autonomic System is Controlled by what?

A

Limbic system, hypothalamus, brainstem and spinal cord

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8
Q

How many Neurons are part of an Autonomic Pathway from the Spinal Cord?

A

Two

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9
Q

In the Autonomic System, are Pre-Ganglionic Nerves Myelinated?

A

Yes

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10
Q

In the Autonomic System, are Post-Ganglionic Nerves Myelinated?

A

No

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11
Q

What do Autonomic Motor Neurons Innervate?

A

Cardiac Muscle, Smooth Muscle and Glands

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12
Q

When an Action Potential reaches an Axon Terminal of a Neuron, what happens?

A

Voltage gated Ca2+ channels open, causing an influx of Ca2+ ions into the axon terminal

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13
Q

What does an Influx of Ca2+ Ions cause in the Pre-Synaptic Neuron?

A

Vesicles containing neurotransmitters to fuse with the plasma membrane, releasing the neurotransmitters into the synaptic cleft

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14
Q

What do the Neurotransmitters released from the Pre-Synaptic Neuron bind to?

A

Ligand gated Na+ channels in the post-synaptic neuron

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15
Q

What does the Binding of Neurotransmitters onto Ligand Gated Na+ Channels in the Post-Synaptic Neuron cause?

A

An influx of Na+ into the post-synaptic neuron, causing the depolarisation of the cell membrane and the creation of an action potential in the post-synaptic neuron

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16
Q

What is another name for the Alarm Response?

A

The “Fight or Flight” response

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17
Q

What happens to our Cardiovascular System during the Alarm Response?

A

Heart rate, heart contraction force and blood pressure increase
Blood vessels (especially in skin) constrict
Blood sugar level also increases

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18
Q

What happens to our Eyes during the Alarm Response?

A

Pupils dilate

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19
Q

What happens within our Digestive system during the Alarm Response?

A

Salivation and other digestive activities decrease to conserve energy

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20
Q

What happens within our Lungs during the Alarm Response?

A

Bronchi dilate to increase capacity for oxygen gas exchange

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21
Q

What happens to the Skin during the Alarm Response?

A

Arrector pili muscles contract and sweat secretion increases from sweat glands

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22
Q

What happens to our Cardiovascular System during the Relaxation Response?

A

Heart rate and force of heart contraction decrease
Peripheral blood vessels dilate

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23
Q

What happens to our Eyes during the Relaxation Response?

A

Pupils contract

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24
Q

What happens within our Digestive System during the Relaxation Response?

A

Salivation and other digestive activities increase

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25
What happens within our **Lungs** during the **Relaxation Response**?
Constriction of Bronchi
26
**Responses** associated with **Exercise, Emotion** and **Excitement** are under the ___ **Division**
**Responses** associated with **Exercise, Emotion** and **Excitement** are under the **Sympathetic** **Division**
27
**Responses** associated with **Repletion, Rest** and **Relaxation** are under the ___ **Division**
**Responses** associated with **Repletion, Rest** and **Relaxation** are under the **Parasympathetic** **Division**
28
What **Neurotransmitter** do both **Sympathetic** and **Parasympathetic** **Pre-Ganglionic Neurons** use?
Acetylcholine
29
What **Neurotransmitter** do **Most** **Sympathetic Post-Ganglionic Neurons** use?
Norepinephrine
30
What **Neurotransmitter** do **Sympathetic** **Post-Ganglionic Neurons** innervating **Sweat Glands** use?
Acetylcholine
31
What **Neurotransmitter** do **Parasympathetic** **Post-Ganglionic Neurons** use?
Acetylcholine
32
Is the **Sympathetic** system always active?
Yes, just turned up and down when needed
33
What is **Raynaud Disease**?
The sympathetic system's inability to deactivate quickly after being stimulated by cold temperatures, resulting in chronic vasoconstriction, causing fingers and toes to become ischemic (lack of blood) and turn white
34
What does the **Hypothalamus** control?
Internal organs via autonomic nervous system and pituitary gland Behavioural patterns, circadian rhythms and sleep/wake cycles Body temperature Eating and drinking behaviour
35
What are the **Main Organs** in the **Endocrine System**?
The hypothalamus, pituitary gland and adrenal glands
36
**Endocrine Hormone** **Target Cells** are typically **Near** or **Far** from the **Endocrine Cell?**
Far, endocrine hormones need to use bloodstream to reach target cells
37
**Paracrine Hormone Target Cells** are typically **Near** or **Far** from the **Paracrine Cell**?
Near, don't typically need to use the bloodstream for hormone to reach target cell
38
What cells do **Autocrine Hormones** affect?
They affect the cell that secreted them
39
**Hormones** can either be **\_\_\_ Soluble** or ___ **Soluble**
**Hormones** can either be **Lipid-Soluble** or **Water**-**Soluble**
40
What do **Lipid-Soluble Hormones** require to pass through the **Blood Stream**?
Transport proteins
41
Can **Lipid-Soluble Hormones** diffuse directly through the **Plasma Membrane**?
Yes
42
Where do **Lipid-Soluble Hormones** typically **Act**?
In the nuclei of target cells, altering gene expression and therefore cell activity
43
Can **Water-Soluble** hormones diffuse through the **Plasma Membrane**?
No
44
After a **Water-Soluble Hormone** binds to a **Receptor** on the surface of a cell, what type of protein is activated?
G-protein
45
What does an **Activated G-Protein** activate?
Adenyl Cyclase
46
What does **Activated Adenyl Cyclase** do?
Converts ATP to cAMP, a second messenger
47
What does **cAMP** do?
Activates protein kinases, which can then phosphorylate other enzymes, causing reactions which induce physiological responses
48
**cAMP** is **Deactivated** by what?
Phosphodiesterase
49
How many different **Hormones** does the **Hypothalamus** secrete to control the **Pituitary**?
Nine
50
How many different **Hormones** does the **Pituitary** secrete to control **Endocrine Organs**?
Seven
51
What connects the **Pituitary** to the **Hypothalamus**?
Infundibulum
52
Which **Blood Vessels** connect the **Hypothalamus** and the **Anterior Pituitary**?
The Hypophyseal Portal Veins
53
What do the **Hypothalamus** and **Pituitary Gland** jointly **Regulate**?
Growth, Metabolism, Development and Homeostasis
54
In the **Adrenal Medulla**, **Sympathetic** **Pre-Ganglionic Neurons** innervate \_\_\_. These cells secrete ___ and ___ into the bloodstream
In the **Adrenal Medulla**, **Sympathetic** **Pre-Ganglionic Neurons** innervate **Modified Post-Ganglionic Neurons** (with no axons). These cells secrete **Epinephrine** and **Norepinephrine** into the bloodstream
55
What do **Epinephrine** and **Norepinephrine** do to the **Alarm Response**?
Maintain and enhance the alarm response
56
What **Hormones** are produced in the **Adrenal Cortex**?
Mineralocorticoids (e.g. Aldosterone) and Glucocorticoids (e.g. Cortisol)
57
What causes **Mineralocorticoid** **Secretion** from the **Adrenal Cortex**?
Increased K+ and angiotensin II in the blood
58
What causes **Glucocorticoid Secretion** from the **Adrenal Cortex**?
Adrenocorticotropic Hormone (ACTH) release from the pituitary gland, Stimulated by Corticotropin releasing hormone (CRH) from the Hypothalamus
59
What do **Mineralocorticoids** do?
Increase blood Na+ and water levels and decrease blood K+ levels, increasing blood volume and pressure
60
What do **Glucocorticoids** do?
Initiate a resistance reaction to stress, dampen inflammation and depress immune responses
61
In relation to **Proteins** (especially in muscle fibres), what does **Cortisol** do?
Induce the breakdown of proteins into amino acids for release into the bloodstream to aid tissue repair, new protein synthesis and ATP production
62
In relation to the **Liver**, what does **Cortisol** do?
Promotes Gluconeogenesis, raising glucose levels for ATP production
63
In terms of **Adipose Tissue**, what does **Cortisol** do?
Promotes triglyceride breakdown and fatty acids to be released into the blood to aid in tissue repair
64
In terms of **Blood Vessels**, what does **Cortisol** do?
Increases sensitivity of blood vessels to vasoconstriction hormones, increasing blood pressure
65
In terms of **Inflammation**, what does **Cortisol** do?
Limits inflammation to limit tissue damage done by white blood cells, which does also slow tissue repair and wound healing
66
In terms of the **Immune System**, what does **Cortisol** do?
It supresses some immune responses
67
In response to **High Blood Cortisol Levels** after the **Removal Of The Stressor**, the **Pituitary Gland** and **Hypothalamus** do what?
The pituitary gland stops secreting adrenocorticotropic hormone (ACTH) and the hypothalamus stops secreting corticotropin releasing hormone (CRH)
68
The **Two Components** of the **Stress Response** are...
1. The Alarm Response (Immediate Sympathetic Nerve Activity and release of Epinephrine and Norepinephrine from the Adrenal Medulla) 2. The Resistance Reaction (Slower and longer lasting hormone driven activity in the Adrenal Cortex, releasing Mineralocorticoids and Glucocorticoids)