Artrita psoriazica Flashcards

1
Q

Prevalenta psoriazis

A

2-3%

10% → artrita psoriazica PRECEDE boala de piele in 15%

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2
Q

Mono / oligo artrita

A
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3
Q

Poliartrita

A

incepe ASIMETRICA → progresie spre simetrica

imposibil de diferentiat de AR

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4
Q

Spondilita

A

sacroilita unilaterala / bilaterala

afectare precoce coloana CERVICALA

50% au HLA-B27

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5
Q

Artrita articulatiilor interfalangiene distale

IFD

A

modelul cel mai tipic

+

adesea - distrofie adiacenta a unghiilor

entezita se extinde in radacina unghiilor

dactilita - intreg deget mana / picior

  • afectarea tecii articulare + tendon
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6
Q

Artrita mutilanta

A

5%

provoaca osteoliza peri-articulara marcata + scurtarea oaselor = DEGETE TELESCOPATE

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7
Q

Radiologic

A

EROZIVA

eroziuni centrale in articulatie, nu juxta-articulare

→ aspect de TOC IN CALIMARA

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8
Q

Boala pielii poate fi

A

usoara

se poate dezvolta dupa aparitia artritei

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9
Q

AINS si analgezice

A

amelioreaza durerea

pot agrava leziunile pielii

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10
Q

Sinovita locala raspunde la

A

injectii intraarticulare cu glucocorticoizi

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11
Q

Sinovita articulara periferica persistenta - cel mai frecv utilizate

A

Metotrexat

Leflunomida

Sulfasalazina

Ma LaSi

niciuna nu are efect dovedit asupra incetinirii dezvoltarii leziunilor articulare

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12
Q

SE EVITA

A

hidroxiclorochina

poate provoca rareori reactii cutanate psoriazice acute

glucocorticoizi orali

pot destabiliza psoriazisul

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13
Q

Medicamente care pot precipita manifestarile cutanate in artrita psoriazica

A

AGHiasma

AINS

Glucocorticoizi

Hidroxiclorochina

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14
Q

Esuat trat cu csDMARD (metotrexat)

A

bDMARD

agenti anti-TNF alfa

ETANERCEPT

GOLIMUMAB

Inhib IL-17

SECUKINUMAB

IXEKIZUMAB

Inhib IL-12/23

USTEKINUMAB

EGSI + U

seggsi u

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15
Q

Esuat trat cu csDMARD

A

tsDMARD

APREMILAST (inhib PDE4)

TOFACITINIB (inhib JAK)

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