Apr10 M3-Eczema and atopy

Question 1

eczema part of what group of diseases and means what

Answer 1

• eczema = synonym for dermatitis

- so is part of papulosquamous diseases

Question 2

(EXAM) characteristic symptom of eczema

Answer 2

ITCHY rash. It’s itchy. pruritus.

Question 3

ACUTE eczema charact

Answer 3

• ill-defined borders (psoriasis = well-defined)
• erythema
• lichenification
• tchy
• laque

Question 4

severe acute eczema can have what

Answer 4

• vesicles, bullae (blisters)

- crusting bc of vesicles rupture

Question 5

thing that can mimic eczema

Answer 5

poison ivy contact

• swollen lesion
• blisters
• very itchy

Question 6

subacute eczema charact

Answer 6

• erythema
• scaling
• bit of crust and no blisters
• dry

Question 7

chronic eczema charact

Answer 7

• lichenification (thickened and accentuated skin markings)

- dry and fissured

Question 8

papular eczema charact and in what type of eczema (acute, subacute, chronic)

Answer 8

• in subacute or chronic
• areas of accentuation of skin follicles
• ITCHY

Question 9

endogenous types of eczema

Answer 9

• atopic dermatitis
• seborrheic dermatitis
• xerotic eczema (caused by dryness)
• nummular eczema (only well-defined one)
• dyshidrotic eczema (palms or soles)
• lichen simplex chronicus (LSC)

Question 10

exogenous types of eczema

Answer 10

• allergic contact dermatitis (cosmetics, etc.)
• irritant contact dermatitis (disinfectants + soap a lot)
• stasis dermatitis (venous insufficiency)
• photo dermatitis (pre-existing and worsens with sunlight)

Question 11

most important form of eczema

Answer 11

atopic dermatitis (is very itchy)

Question 12

(EXAM) atopic triad in atopic dermatitis

Answer 12

• eczema
• asthma
• rhinitis

Question 13

causes of atopic dermatitis

Answer 13

• genetics**

- allergies

Question 14

atopic dermatitis pathogenesis

Answer 14

• genetic, immuno and environment influence + bad skin barriers so allergens get in
• hypersensitivity, NOT allergy
• th2 activation pakes IgE and eosinophilia
• later th1 with IL-2, IFN-g and IL-12

Question 15

(imp?) major criteria for atopic dermatitis

Answer 15

• pruritus
• typical morphology and distribution
• chronic or chronically-relapsing
• personal or family Hx of asthma or allergic rhinitis or atopic dermatitis

Question 16

eczema distribution with age

Answer 16

• infancy = face**, trunk, back, legs, not genitalia
• childhood = legs and arms
• adulthood = hands, feet and elbows

Question 17

juvenile plantar atopic dermatitis subtype charact

Answer 17

• childhood to early teen subtype
• in sole of the foot
• peeling glazed aspect
• associated with sweaty feet

Question 18

charact of atopic dermatitis in adults

Answer 18

• can be anywhere
• women = eyes bc cosmetics
• hyperlinearity if on the fingers
• NO OIL DROP LIKE NAILS

Question 19

atopic dermatitis tx

Answer 19

• good skin care. MOISTURIZE to prevent
• Tx: topical steroid + moisturize
• decrease exposure to irritants
• lukewarm water for bath and shower
• bleach bath
• sedating antihistamines through the night (avoid scratching)

Question 20

acute atopic dermatitis tx

Answer 20

• saline on blisters
• strong topical CS
• systemic Abx if 2ndary infection

Question 21

subacute atopic dermatitis tx

Answer 21

• mid-potency CS

- topical calcineurin inhibitors

Question 22

chronic atopic dermatitis tx

Answer 22

• calcineurin inhibitors
• topical CS
• phototherapy or immunosuppressives if severe