Apr10 A1-Vasculitis Case Conference Flashcards

1
Q

2 common features of CT disease (autoimmune)

A
  • polyneuritis (inflam of peripheral nerves)

- arthralgia

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2
Q

(EXAM) one large vessel vasculitis

A

giant cell arteritis

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3
Q

(EXAM) one medium sized vessel vasculitis

A

polyarteritis nodosa

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4
Q

(EXAM) two small vesels vasculites

A
  • granulomatosis with polyangiitis (Wegener’s granulomatosis)
  • microscopic polyangiitis
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5
Q

(EXAM) giant cell arteritis clinical manifestations

A
  • polymyalgia rheumatica

- occular manifestations (diploplia, blindness)

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6
Q

(EXAM) polyarteritis nodosa clinical manifestations

A
  • abdominal pain and melena
  • peripheral neuritis (polyneuritis)
  • hypertension
  • relapsing and remitting disease*
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7
Q

(EXAM) granulomatosis with polyangiitis clinical manifestations

A
  • sinusitis, rhinitis
  • cavitated lung nodules
  • glomerulonephritis
  • c-ANCA positive Abs. (PR3-ANCA proteinase 3)
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8
Q

(EXAM) microscopic polyangiitis clinical manifestations

A
  • glomerulonephritis
  • pulmonary hemorrhage
  • p-ANCA positive Abs. (MPO-ANCA myeloperoxidase)
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9
Q

(EXAM) specific Ab found in granulomatosis with polyangiitis

A

c-ANCA (PR3 proteinase 3)

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10
Q

strong underlying cause of polyarteritis nodosa

A

hep B infection

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