antivirals Flashcards
the envelope is the outermost layer of a _______. Composed of elements of the host cell ______
virus
membrane/ER/or nuclear envelope
the capsid is the second layer in. Protects the _________
viral nucleic acid
a virus can have ____, ____, or both
DNA
RNA
antiherpetic agents target viruses in the ________
herpesviridae family
________ is an antiherpetic that treats HSV-2
acyclovir
primary infection, latency, and recurrence are characteristic of _____
herpesviridae
acyclovir (trade name is _____) requires dosing ___ - ___ times a day. There are ___ DR, but GI disturbances and _____ are ADRs
zovirax
4-5
no
hepatotoxicity
what drug is a nucleoside analog that halts DNA replication?
acyclovir
neuroaminidase inhibitors are used for _________
anti-influenza
antiretroviral drugs are focused on _____
HIV
HIV requires a complex ______ ____ which consists of at least 3 drugs
complex multidrug
HIV drugs generally inhibit the virally-encoded protein _____ _____
reverse transcriptase
antiviral interferons are normal human ______ used by the immune system to activate cells when infection is present
cytokines
______ is worrisome from Ribavirin
hemolytic anemia
ribavirin is used in the treatment of _______ and respiratory syncytial virus
HCV