antivirals Flashcards

1
Q

the envelope is the outermost layer of a _______. Composed of elements of the host cell ______

A

virus

membrane/ER/or nuclear envelope

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2
Q

the capsid is the second layer in. Protects the _________

A

viral nucleic acid

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3
Q

a virus can have ____, ____, or both

A

DNA

RNA

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4
Q

antiherpetic agents target viruses in the ________

A

herpesviridae family

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5
Q

________ is an antiherpetic that treats HSV-2

A

acyclovir

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6
Q

primary infection, latency, and recurrence are characteristic of _____

A

herpesviridae

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7
Q

acyclovir (trade name is _____) requires dosing ___ - ___ times a day. There are ___ DR, but GI disturbances and _____ are ADRs

A

zovirax
4-5
no
hepatotoxicity

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8
Q

what drug is a nucleoside analog that halts DNA replication?

A

acyclovir

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9
Q

neuroaminidase inhibitors are used for _________

A

anti-influenza

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10
Q

antiretroviral drugs are focused on _____

A

HIV

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11
Q

HIV requires a complex ______ ____ which consists of at least 3 drugs

A

complex multidrug

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12
Q

HIV drugs generally inhibit the virally-encoded protein _____ _____

A

reverse transcriptase

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13
Q

antiviral interferons are normal human ______ used by the immune system to activate cells when infection is present

A

cytokines

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14
Q

______ is worrisome from Ribavirin

A

hemolytic anemia

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15
Q

ribavirin is used in the treatment of _______ and respiratory syncytial virus

A

HCV

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