Antivirals

Question 1

Selzentry

Answer 1

Binds to HIV receptors on host cells preventing attachment

Question 2

Docosanol (Abreva)

Answer 2

a fatty acid becomes incorporated in the host cell membrane preventing herpes fusion with the host

Question 3

Amandatide

Answer 3

binds to the influenza virus’s capsid preventing release of NA

Question 4

Pleconaril

Answer 4

binds to the ronovirus’s capsid preventing the release of NA

Question 5

Foscarnet

Answer 5

Binds to DNA polymerase preventing the production of new viral DNA
- effective on cytomegalovirus, and herpes simplex virus

Question 6

Acyclovir

Answer 6

A prodrug that is metabolized into a guanine analog that inserts itself into replicated DNA preventing further replication of Herpes simplex virus

Question 7

Azidothymidine

Answer 7

A thiamyne analog that inserts itself into replicated viral DNA preventing further replication of HIV

Question 8

Ritonavir, Saquinavir

Answer 8

Protease inhibitors - inhibit protease activity which prevents final viral assembly of HIV

Question 9

Oseltamivir (Tamiflu), Zanamivir (Relenza)

Answer 9

Neuraminidase inhibitors - inhibit enzyme activity which prevents release of the influenza virus

Question 10

INF

Answer 10

peptides released by infected cells which stimulate release of antiviral agents by neighboring cells