Antifungals

Question 1

Polyenes

Answer 1

Bind to ergosterol creating pores in the fungal membrane that result in cytoplasmic leakage

Question 2

Azoles

Answer 2

Chemicals which block ergosterol synthesis leading to cytoplasmic leakage, including imidazoles, triazoles, and terbinofine

Question 3

Nucleotide Analogues

Answer 3

The drug is transported into the cell by a membrane transporter, where it is metabolized into an analogue and prevents further synteshis of the nucleotide