Antitussives Flashcards

1
Q

En que casos devemos de recetar antitusivos

A

Para tos crónica y tos no asociada a enfermedad

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2
Q

Antitusivos comunes

A

Dextrometorfano, Benzonato, Guaifenesina y ambroxol

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3
Q

EA del Dextrometorfano

A

Náusea, vómito, mareo, sedación.

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4
Q

Indicaciones del Dextrometorfano

A

Tos irritativa

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5
Q

ADME del Dextrometorfano

A

Administración oral. Inicio de acción 15-30 min. Pico 2-3 h

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6
Q

MoA del Dextrometorfano

A

Agonista opioide - inhibe el centro de la tos en bulbo raquídeo

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7
Q

MoA del Benzonatato

A

Anestésico que inhibe activación de terminaciones nerviosas bronquiales

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8
Q

EA del Benzonatato

A

Cefalea, erupción cutánea, sedación.

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9
Q

ADME del Benzonatato

A

Administración oral. Inicio de acción 15-20 min. Pico 3 - 8 h

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10
Q

indicaciones del Benzonatato

A

Tos irritativa

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11
Q

Consideraciones del Benzonatato

A

No masticar cápsulas ya que puede anestesiar la boca y laringe (peligroso)

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12
Q

MoA de la Guaifenesina y ambroxol

A

Desconocidos -> ⬇️ viscocidad de secreciones; ⬆️ de barrido mucociliar

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13
Q

Indicaciones de la Guaifenesina y ambroxol

A

Tos productiva (expectorante)

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14
Q

EA de la Guaifenesina y ambroxol

A

Mareo, náuseas, vómito, dolor abdominal.

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15
Q

Consideraciones de la Guaifenesina y ambroxol

A

No hay estudios mostrando efectividad.

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