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Antimicrobials > Antiprotozoal > Flashcards

Antiprotozoal Flashcards

1
Q

Classification

A

Tissue amebicides; metronidazole,tinidazoles, emetine etc
Luminal amebicides; tetracyclines, hydroxyquin etc

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2
Q

Metronidazole MOA?

A

Becomes a Radical after entering cell and damages DNA

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3
Q

Metronidazole excreted via

A

Liver

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4
Q

Metronidazole ADRs?

A

Anorexia
Metallic taste
Peripheral neuropathy
Seizure
Glossitis, dry mouth, rash etc

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5
Q

Metronidazole CLINICAL USES

A

GET (giardiasis, entamoeba, Trichomias)
Pseudomembranous colitis
H pylori
Ulcerative gingivitis

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6
Q

Metronidazole contraindicated?

A

Pregnancy (1st trimester)
Alcoholic
Neurological disease

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7
Q

Interactions of metronidazole

A

Alcohol
Warfarin
Cimetidine
Anti-epileptic

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8
Q

Metronidazole is a derivative/prototype of

A

Nitroimidazole

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Antimicrobials (9 decks)

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