antiplatelets Flashcards
What do antiplatelet do?
prevention clot formation by preventing platelet aggregation. lowers platelet aggregation to have less chance of them sticking together clogging the artery.
Plavix
Clopidrogrel
Ticilid
Ticlopidine
Aggrastat
Tirofiban
Dipyridamole
Persantine
Aggrenox
Dipyridamole + ASA (ACETYLSALICYLIC ACID)
what is antiplatelets used for?
used for post coronary intervention (PCI) aka cath lab to clear the clot.
Also used for an MI, CVA, TIA (brain), acute coronary syndrome, PAD. Prevention after stent or bypass surgery placement. prevents occlusion of that artery.
Aspirin
Salicylate acid
common side effects:
bleeding nausea stomach pain rash and itching upset stomach diarrhea headache
Nursing interventions:
avoid if allergic to aspirin, ibuprofen, or naproxen (nsaids)
- hold 7 to 8 days before surgery (1 week).
- use caution during activities requiring alertness (such as driving a car)
- teach: monitor for signs of bleeding
- do not use any other over the counter (OTC) medication
- avoid use of aspirin, salicylates, and NSAID’s while taking these medications.
- AVOID IN PREGNANCY
KEY NUMBERS TO ASSESS for when on anti-platelets
1.) hemoglobin less than 7
2.) platelets less than 150,000 risky notify HCP
less than 50,000 very risky
3.) Thrombocytopenia= lower platelet count
these medications should not decrease platelet count so question the order.
what to do if you have a platelet count of 75,000 or 40,000 priority?
- ) hold the drug
- ) question the drug
- ) notify HCP
What is the #1 drug given for aspirin toxicity?
ACTIVATED CHARCOAL
WHAT IS THE initial treatment for salicylate toxicity?
activated charcoal
what are key signs of aspirin toxicity?
- ) tinnitus= ringing of the ears
2. ) hyperventilation=notify HCP immediately
what can indicate salicylate toxicity?
hyperventilation
what is contraindicated with aspirin?
hypoprothrombinemia=low clotting factors
what to assess with long term aspirin use?
ASSESS FOR TINNITUS “RINGING IN THE EAR”!!!
What are glycoprotein receptor blockers? aka
IIb/IIIa receptor antagonists
antiplatelet such as:
ABCIXIMAB
EPTIFIBATIDE
TIROFIBAN
What do ABCIXIMAB
EPTIFIBATIDE
TIROFIBAN do?
glycoprotein receptor blockers that are mainly used after cardiac procedures like heart cath or coronary stent placement. it prevent vessel reocclusion.
what are adverse effects of abciximab or glycoprotein receptor blockers? aka
IIb/IIIa receptor antagonist
- thrombocytopenia=low platelet count
- bleeding
action the nurse should implement with glycoprotein receptor blockers? aka
IIb/IIIa receptor antagonist
1.) assessment of hemoglobin less than 7, platelet less than 150,000 alert HCP, or less than 50,000 very risky.
2.) assess for bleeding like:
hematuria= blood in urine
dark tarry stools/black or bloody stools.
- ) place on a cardiac monitor to look for ECG CHANGES
- ) monitor groin insertion site for s/s of bleeding after percutaneous coronary insertion (PCI).
what should be avoided in glycoprotein receptor blockers? aka
IIb/IIIa receptor antagonist
AVOID NEW NEEDLES. IM INJECTIONS, OR IV INJECTIONS=during and after administration.