anticoagulants Flashcards

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1
Q

what do anticoagulants do?

A

prevent blood clotting. It withholds coagulation factors

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2
Q

why are anticoagulants given? key word?

A

prevention of new clots and preventing existing clots. specifically with patients recovering from an mi heart attack or those at risk for a DVT like after a hip or knee surgery

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3
Q

what dissolves clots?

A

thrombolytics like TPA and alteplase

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4
Q

do anticoagulants dissolve clots?

A

no only thrombolytics do this

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5
Q

what do anticoagulants block?

A

fibrin

anticoagulation withholding clotting factors in the coagulation cascade mainly blocking the formation of fibrin since fibrin forms the seals on the clock.

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6
Q

what is the difference between warfarin and heparin?

A

heparin works quickly and can only be injected like IV or SQ into the patient like enoxaparin or Lower weight molecular heparin.

warfarin works slowly it takes 5 days to start working. BUT IT LASTS LONGER AND CAN BE TAKEN LONGER.

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7
Q

What is the key word for heparin and warfarin being taken at the same time?

A

BOTH MEDICATIONS ARE GIVEN TOGETHER FOR SEVERAL DAYS

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8
Q

Anticoagulant labs:

A

IF THEY ARE TOO HIGH THE PATIENT WILL BLEED OUT AND DIE

BUT IF THEY ARE TOO LOW THE RISK FOR CLOTTING GROWS

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9
Q

Labs to know for heparin?

A

PTT: 46 TO 70

ANYTHING MORE THAN 70 Hold medication

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10
Q

what is the antidote for heparin?

A

PROTAMINE SULFATE

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11
Q

Heparin drip PTT 85 or 100?

A

PTT IS OVER 70 so the priority is?
1.) stop the heparin drip and notify HCP

  1. ) Prepare antidote protamine sulfate
  2. ) reassess labs in 1 hour
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12
Q

if their is a patient on a heparin drip with bleeding at the iv site or “BLOOD OOZING AT THE SURGICAL INCISION”?

A
  1. ) Stop the infusion and notify HCP
  2. ) ADMINISTER protamine sulfate
  3. ) reassess labs in 1 hour
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13
Q

labs for warfarin?

A

INR 2 to 3

heart valve replacements: 2.5 to 3.5

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14
Q

what is the antidote for warfarin? and where is it found?

A

vitamin k

seen in liver and green leafy vegetables like broccoli and spinach

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15
Q

when can vitamin K not be given?

A

when warfarin is in therapeutic range

at least 5 days on warfarin therapy when switching to IV heparin

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16
Q

what is patient teaching on vitamin k and warfarin?

A

consistency and moderation
DO NOT INCREASE
DO NOT DECREASE
DO NOT AVOID TOTALLY

NICE CONSISTENCY MODERATION

17
Q

What does the statement I will increase my intake of dark green leafy vegetables mean?

A

requires intervention since it has to be a nice consistency in moderation

18
Q

ANTIBIOTICS INCREASE THE RISK OF BLEEDING!!!

A

since it INCREASES the INR. SINCE ANTIBIOTICS KILLS THE intestinal bacteria that produces vitamin K that ends up with a vitamin K deficiency, which increases the risk for bleeding.

19
Q

what do you do when you are on warfarin with an IINR of 4 or 5?

A
  1. ) assess for bleeding

2. ) get vitamin K antidote ready

20
Q

what to do if your INR is 2.0 and your patient has ischemic CVA?

A

administer warfarin so that it increases to 2.5

21
Q

Warfarin patient teaching?

A
  1. ) Taken LIFE LONG to prevent clots like in patients with:
  2. ) -atrial fibrillation
    - artificial heart valve replacements typically more prevalent in key term -mechanical valve replacements.

3.) FREQUENT BLOOD TESTS to check the therapeutic range

22
Q

what requires frequent blood tests?

A

WARFARIN ONLY

23
Q

how long is heparin given for? and what is is usually given IV?

A

A few days or a few weeks

usually given after an mi heart attack or a Pulmonary embolism in the lung to prevent the clot from growing

24
Q

What do heparin SQ end in? and what are they called?

A

parin like:
enoxaparin
Dalteparin

LESS CHANCE OF BLEEDING
LOWER WEIGHT MOLECULAR HEPARIN

25
Q

What is the key term as to why heparin SQ is given?

A

PREVENTION OF CLOTS AFTER SURGERY

26
Q

How is SQ heparin administered?

A
  1. ) 25 GAGE NEEDLE with 5/8 inch
  2. ) 90 DEGREE ANGLE
  3. ) 2 inches from the UMBILICUS

NEVER THE THIGH JUST THE UMBILICUS

27
Q

what should NEVER be done with LMW heparin injections?

A
  1. ) NEVER ASPIRATE SQ injection

2. ) NEVER RUB THE SITE

28
Q

what is a normal finding after a SQ injection?

A

NORMAL TO HAVE MILD PAIN, BRUISING, IRRITATION, REDNESS AT THE SITE

AN ICE CHIP CAN BE APPLIED tp help with irritation

29
Q

LWM heparin assessment priority?

A
  1. ) assess hemoglobin and hematocrit before giving to patient with open fractures
  2. ) Notify HCP and clarify order for enoxaparin if H/H slightly low.
30
Q

When a patient is on enoxaparin when should the HCP be notified for clarification of order?

A
  1. ) H/H SLIGHTY LOW

2. ) blood PRESSURE DROPS BY 20 POINTS

31
Q

WHAT Labs are taken for LWMH like enoxaparin?

A

1.) Low platelets =FOCUS ON PLATELETS

32
Q

Key numbers for LMWH?

A

1.) platelets between 150,000 to 400,000

33
Q

When should LMWH be hold?

A

platelets less than 50,000

34
Q

what is a major risk of LMWH like enoxaparin and dalteparn?

A

HEPARIN INDUCED THROMBOCYTOPENIA

when the platelet count drops by half WITHIN 24 hours after giving any type of heparin!!!

35
Q

What is the priority action for HIT?

A

Alert the HCP

36
Q

what should be avoided when on warfarin?

A

caffeine such as coffee and teas

ethanol which is found in alcohol