Antinematodal Drugs Flashcards

1
Q

Benzimidazoles: spectrum, side effect

A

Most nematodes, Taenia spp. tapeworms

Rare bone marrow toxicity - usually dose dependant

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2
Q

Fenbendazole: name brands (2), type, species, spectrum

A

Panacur, Safeguard

Benzimidazoles

All domestic species

Also covers Giardia, Flukes

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3
Q

Fenbandazole: type, metabolites (2), species, formulation

A

Benzimidazole

Metabolized into Fenbendazole and Oxfendazole

Dogs and cats

Only found in DrontalPlus combination dewormer

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4
Q

Albendazole: type, species, spectrum

A

Benzimidazole

LA

Also covers flukes

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5
Q

Oxfendazole: type, species

A

Benzimidazole

LA

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6
Q

Oxibendazole: type, species

A

Benzimidazole

LA

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7
Q

Pyrantel Tartrate: spectrum

A

Some nematodes, equine tapeworms

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8
Q

Pyrantel pamoate: brand names (2), spectrum, species

A

Nemex, Strongid

Some nematodes, equine tapeworms

SA, equine, exotics

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9
Q

Emodepside: brand name, type, spectrum, species, administration

A

Profender - combined with praziqiantel

Depsipeptide

Nematodes and tapeworms

Cats

Topical

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10
Q

Macrocyclic Lactones: spectrum, administration (3)

A

Some nematodes, some arthropods

Oral

Injectable

Topical

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11
Q

Macrocyclic Lactones: caution

A

MDR1 mutation dogs have increased sensitivity

Heartworm doses are safe

Higher deworming doses can cause neurological signs

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12
Q

Ivermectin: type, species, administration (3), caution

A

Macrocyclic Lactone

Most domestic and some exotic species

PO

Injectable

Topical

Don’t use injectable products in horses

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13
Q

Ivermectin and SA Manage: administration, caution

A

Injectable LA products are used PO

ELDU

Dogs must be MDR1 neg or have dose titrated and observed carefully

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14
Q

Moxidectin: type, species, administration

A

Macrocyclic Lactone

Most domestic and some exotic species

PO

Injectable

Topical

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15
Q

Doramectin: type, species

A

Macrocyclic Lactone

Food animals

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16
Q

Eprinomectin: type, species

A

Macrocyclic Lactone

Food animals and cats

17
Q

Macrocyclic Lactone HWP: spectrum, administration

A

L3 and L4 heartworm larva

Some formulations also kill L1 microfilaria

Nematodes, some ectoparasites

Oral

Injectable

Topical

18
Q

Melarsomine: brand name, spectrum, species, administration

A

Immiticide

L5 and adult heartworms only

Dogs

IM in epaxials only

19
Q

Melarsomine: side effect, caution

A

Narrow therapeutic index (it’s arsenic!)

Tenderness and inflammation at injection site

Strict exercise restriction for at least 4 weeks post tx to prevent thromboembolism