Antimycobacterials Flashcards
0
Q
Butanol derivative
A
E
1
Q
Nicotinic acid derivative
A
H
2
Q
Inhibits mycolic acid synthesis
A
H
3
Q
Inhibits DNA dependent DNA polymerase
A
R
4
Q
Inhibits arabynosyl transferases involved in synthesis of arabinoglycan in mycobacterial cell wall
A
E
5
Q
Unknown MOA
A
Z
6
Q
Inhibit protein synthesis by binding to 30s subunit
A
S
7
Q
Most important virulence factor of TB
A
Cord factor/trehalose mycolate
8
Q
Bactericidal
A
HRS Z (may be static)
9
Q
SE of isoniazid
A
Hepatitis
Neurotoxicity
Hemolysis in G6PD
Drug-induced lupus
11
Q
SE: red orange urine
A
R
12
Q
SE: hepatotixicity
A
H<Z
13
Q
SE: color blindness (what kind?)
A
E (red green)
14
Q
SE of Z
A
Hepatotoxicity
Hyperuricemia
16
Q
For TB prophylaxis
A
H
