Antiamebiasis Flashcards
Tissue amebecides
Chloriquine
Emetine
Metronidazole
Nitazoxanide
Luminal amebecides
Dilozanide furoate
Iodoquinol
Paromomycin
DOC for asymptomatic cyst carriers
Diloxanide furoate
Back up drug for severe intestinal and extraintestinal amebiasis
Emetine
For mild to severe intestinal amebiasis used in combination with metronidazole
Iodoquinol
Reactive reduction bu ferredoxin forming free radicals that disrupt te ETC
Metronidazole
Nitazoxanide
Inhibits protein synthesis bu blocking ribosomal movement along mRNA
Emetine
Inhibits protein synthesis by binding to 16s ribosomal subunit
Paromomycin
DOC for cryptosporpidiosis
Nitazoxanide
Causes muscle weakness, CV dysfunction (arrhythmias, CHF)
Emetine
Causes thyroid enlargement
Iodoquinol
DOC for severe intestinal and extraintestinal amebiasis
Metronidazole
Backup for asymptomatic cyst carriers
Paromomycin
DOC for cryptosporoidiosis
Nitazoxanide