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Pharma > Antihelminthic > Flashcards

Antihelminthic Flashcards

0
Q

DOC for trichuris

A

Mebendazole

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1
Q

Coverage of albendazole

A

Ascariasis
Ancylostoma
Necator
Capillariasis

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2
Q

DOC for strongyloides

A

Ivermectin

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3
Q

DOC for enterobius

A

Pyrantel pamoate

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4
Q

DOC for filariasis

A

DEC

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5
Q

DOC for trichinella

A

Thiabendazole

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6
Q

Selectively inhibits microtubule synthesis and glucose uptake in nematodes

A

Mebendazole

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7
Q

Inhibits microtubule assembly

A

Albendazole

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8
Q

Intensifies GABA-mediated neurotransmission in nematodes

A

Ivermectin

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9
Q

Stimulates nicotinic receptors at NMJ of nematodes

A

Pyrabtel pamoate

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10
Q

Selectively inhibits microtubule synthesis and glucose uptake in nematodes

A

Thiabendazole

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11
Q

Invreases membrane permeability to calcium causing muscle paralysis, vacuolization and death

A

Praziquantel

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12
Q

Uncouples oxidative phosphorylation by activating ATPases

A

Niclosamide

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13
Q

Differentiate mebendazole, thiabendazole and albendazole in terms of _-cidal

A

Meb: Ovicidal
Thia: Ovicidal
Alb: Larvicidal and ovicidal

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14
Q

DOC for echinococcus

A

Albendazole

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15
Q

Mazzoti reaction is seen in

A

DEC in filariasis

Ivernmectin in strongyloidiasis

16
Q

Contraindicated in pregnancy

A

Mebendazole

Thiabendazole

17
Q

Contraindicated in patients with hepatic dysfunction

A

Pyrantel pamoate

18
Q

Praziquantel is used with _ in treating neurocysticercosis

A

Corticosteroids

19
Q

CI of praziquantel

A

Ocular cystecircosis

20
Q

Alternative drug for cestode infection

A

Niclosamide

21
Q

Kills scolices and cestode segments but has no effect on ova

A

Niclosamide

22
Q

Avoid _ with niclosamide

A

Alcohil consumption for 48h upon administration

23
Q

Wide activity against nematodes killing adult worms in the colon but not the eggs

A

Pyrantel pamoate

24
Q

Causes SJS

A

Thiabendazole

Pharma (11 decks)

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