Antimicrobial use ICU ASSA

Question 1

Prophylaxis ?
what is approach ?

How long to give prophylaxis ?
When to repeat ?

Answer 1

Question 2

Treatment : Approach ?
Duration ?
How long treatment for intra abdominal sepsis ?
Role of PCT ?
Extended courses?

Answer 2

5-7 post source control for intra abdominal sepsis

Reduction of PCT

Stap pneumonia -7-14 days

Staph bacteremia 2/52 post neg bloodculture
need at least 2/52 treatment

Two weeks post removal of graft if graft can be removed
6/52 if not be removed

OM 2/52 to lifelong

Question 3

Micro approach

Answer 3

Question 4

Specific to organ micro ?

Answer 4

Question 5

Name examples of drugs used dosing ?
concentration dependent ?
vs time dependent ?
AUC ?

MIC ?

Answer 5

Question 6

Resistance MOA ?

Answer 6

Question 7

moa of AB
5 GROUPS ?

Answer 7

Question 8

Pennicilin group ? 3

Answer 8

Question 9

Co amoxiclav vs Pip taz

Answer 9

Question 10

Cephalosporin ?

Answer 10

Question 11

Carbapenems ?

How many generations ?
Special considerations ?

Answer 11

Question 12

Glycopeptide
MOA ?

examples

Risks ?

Answer 12

Question 13

Inhibitors protein synthesis

Answer 13

Question 14

Inhibitors of cell membrane function

Answer 14

Question 15

Sulphonamides

Answer 15

Question 16

Inhibitors of nucleic acid synthesis