AKI -Acute kidney injury John A. and 2016 AKI Flashcards
Def
AKI
AKD
CKD
NKD
Causes of AKI
Pre renal
Renal
Post renal
Community vs Hospital acquired ?
Different causes for low vs high income ?
Pathophysiology ?
What is effects on ?
Fluid homeostasis :
K ?
Na ?
Phosphate ?
Acid base ?
Fixed acids ?
Aninon gap ?
Importantly, kidney failure affects most organ systems
of the body?:
GIT
Lungs
Cardiac
CNS
Def AKI ?
The term AKI, as defined, ascribes a decline in kidney
excretory function and frequently (but not always)
also tissue injury.
Management
Volume status ?
Haemodynamic ?
Nephrotoxic drugs ?
Diagnosis of AKI
Accordingly, AKI is
diagnosed if serum creatinine increases by 0.3 mg/dl
(26.5 μmol/l) or more in 48 h or rises to at least 1.5-fold
from baseline within 7 days (Table 1
Diagnosis of acute kidney disease ?
Most common causes of AKI in critically ill ?
As a syndrome, AKI can have multiple aetiologies. In
critically ill patients, the most common causes are sepsis,
heart failure, haemodynamic instability, hypovolaemia,
and exposure to nephrotoxic substances [
Classify AKI causes
prev pre renal renal and post renal ?
Workup algorithm ?