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F2 > Antiepilepticos > Flashcards

Antiepilepticos Flashcards

1
Q

crisis epileptic

A

justo en el momento en el que se presenta

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2
Q

Estado epiléptico

A

Crisis que dura varios minutos

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3
Q

Crisis focales

A

Con o sin alteraciones de alerta

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4
Q

Crisis generalizadas

A

tonico clonicas
ausencias
atonicas
miclonicas

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5
Q

Que pasa en cada fase de las convulsiones tónico-clonicas

A

fase tonica: musculos tensos
fase clonica: relajacion y contracción rapida

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6
Q

farmacós que su principal MA en bloqueo de canales de Na

A

FEnitoina
carbamazepine
valproate
lamotrigine
topiramato

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7
Q

MA de Fenitoina

A

Bloquea Na y prolonga estado inactivo

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8
Q

Indicaciones generales de Fenitoina

A

Todos los tipos de epilepsia
Status epilepticus

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9
Q

EA de Fenitoina

A

Hitruismo
hiperplasia gingival

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10
Q

Contraindicaciones de fenitoina

A

Anticonseptivos aumentan su metabolismo
no crisis de ausencia

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11
Q

MA de carbamazepine

A

Modulador de Na y ca
Inhiben transmisión de glutamato

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12
Q

IG de carbamazepine

A

Crisis focales
Neuralgia del trigemino

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13
Q

FC de carbamazepine

A

Inductor de muchos sustratos
Induce su propio metabolismo

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14
Q

EA de carbamazepina

A

Toxicidad hematología
hepatotoxic
Sx DRESS
No embarazadas

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15
Q

MA de lamotrigine

A

Modula Na y ca
Inhibe liberación de glutamato
Potencia GABA

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16
Q

IG lamotrigine

A

Tonico clonicas
Bipolaridad

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17
Q

EA lamotrigine

A

Sx Steven Johnson
Necrosis epidermica grave
Categoria C

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18
Q

Contraindicaciones de lamotrigine

A

No en px con insuficiencia hepática

19
Q

MA topiramato

A

Bloqueo NA, ca y GAbA
Bloqueo receptores Ampa y Kainato

20
Q

Indicaciones generales topiramate

A

Coadyuvante
1ra linea profilaxis migraña

21
Q

EA topiramato

A

ataxia
mareos
somnoliencia
piedras en riñones

22
Q

Contraindicaciones de topiramate

A

No crisis ausencia
Categoría X (fisura palatina RN)

23
Q

MA Valproato

A

Modula Na y Ca
aumenta tono gabanergico
inhibe glutaminergica

24
Q

IG valproate

A

Tonico clonicas
Ausencias
Miclonicas
Migraña
bipolaridad

25
Q

EA de valproate

A

Alopécia
Hepatotoxic
Ganancia de peso
Categoria X

26
Q

Farmacós que su principal MA de bloqueo de canales de Ca

A

Etosuximida
Levetiracetam

27
Q

MA de etosuximida

A

Modula canales Ca en talamo y nucleo subtalamicos

28
Q

Indicaciones generales de etosuximida

A

1ra linea Crisis ausencia

29
Q

EA etosuximida

A

Sintomas etrapiramidales
Steven Johnson

30
Q

Contraindicaciones etosuximida

A

puede empeorar crisis tonico clonicas
Clategoria C (3meses embarazo)

31
Q

MA levetiracetam

A

Imbibe canales Ca
Bloqueo SV2A (modula gaba y liberación de glut )

32
Q

IG de levetiracetam

A

1ra linea crisis parciales

33
Q

EA levetiracetam

A

Sintomas psiquiátricos

34
Q

Farmacós que inhibe GABA

A

tiagabina
Vigabatrina

35
Q

IG tiagabina

A

crisis focales

36
Q

EA tiagabina

A

Insomnio
cambios de peso

37
Q

MA vigabatrina

A

Inhibe gaba transaminasa irreversível

38
Q

IG Vigabatrina

A

Monoterapia espasmos infantiles
Crisis focales retardadas
Coadyuvante

39
Q

EA de Vigabatrina

40
Q

Gabapentinoides

A

Pregabalina y gabapentin

41
Q

MA de gabapentinoides

A

Inhiben canales presinapticos P/Q
Regulan la entrada de calcio en a2delta

42
Q

IG gabapentinoides

A

Crisis focales, dolor neuropathic, TAG

43
Q

EA gabapentinoides

A

Somnoliencia
ataxia
ganancias de peso

44
Q

Contraindicaciones de Gabapentina

A

Morfina incrementa sus concentraciones

F2 (15 decks)

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