Antiemetics, serotonin 5-HT3-receptor antagonists Flashcards
1
Q
What is it indicated for?
A
Prophylaxis and treatment of nausea and vomiting
2
Q
How does it work?
A
Blocks serotonin in the nausea and vomiting pathways
3
Q
What are the side effects of these drugs?
A
Constipation
Headache
Flushing
May prolong QT interval
4
Q
What are the warnings of this drug class?
A
Prolonged QT interval use in caution
Ondansetron not recommended in first trimester
5
Q
What are the important interactions of this drug class?
A
Drugs that prolong QT interval such as antipsychotics, quinine, and selective serotonin reuptake inhibitors.
6
Q
What are the names of drugs in this class?
A
ondansetron, granisetron