Antiemetics, serotonin 5-HT3-receptor antagonists Flashcards

1
Q

What is it indicated for?

A

Prophylaxis and treatment of nausea and vomiting

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2
Q

How does it work?

A

Blocks serotonin in the nausea and vomiting pathways

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3
Q

What are the side effects of these drugs?

A

Constipation
Headache
Flushing
May prolong QT interval

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4
Q

What are the warnings of this drug class?

A

Prolonged QT interval use in caution
Ondansetron not recommended in first trimester

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5
Q

What are the important interactions of this drug class?

A

Drugs that prolong QT interval such as antipsychotics, quinine, and selective serotonin reuptake inhibitors.

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6
Q

What are the names of drugs in this class?

A

ondansetron, granisetron

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