Antibodies Flashcards
rheumatoid arthritis
RF, anti-CCP
SLE
ANA, anti-dsDNA, anti-Rho, anti-La
Raised ESR or PV
drug induced: anti-histone
polymyalgia rheumatica
ESR or CRP
spondyloarthropathies
HLA-B27 gene
Ankylosing spondylitis- raised CRP
Psoriatic arthritis- CRP raised
Reactive arthritis- CRP raised
sjogrens
anti-ro and anti la
RF and anti ds-DNA
vasculitis
ANA, ANCA, RF
C3, C4
granulomatosis with polyangiitis (Wegeners)
cANCA
eosinophilic granulomatosis with polyangiitis (Churg strauss)
pANCA
systemic sclerosis
limited- Anti-centromere
systemic- scl-70 (topoisomerase)
autoantibodies found in raynauds
look for antibodies associated with:
scleroderma, SLE, dermatomyositis and polymyositis, Sjoren’
osteoporosis DEXA
-2.50
osteopenia if ,-1-2.5
autoantibody for autoimmune hepatitis
anti-smooth muscle
autoantibody for autoimmune hepatitis
anti-smooth muscle
autoantibody for autoimmune hepatitis
anti-smooth muscle
diffuse systemic scleroderma
Scl-70 (topoisomerase) and anti RNA polymerase III
Bowel cancer
CEA
Pancreatic/ cholangio cancer
CA 19-9
liver cancer
AFP
Alphafetoproetin
high output stoma management
- restrict hypotonic solution
- give dextrose saline
- Antimotility drug- give loperamide (instead of codeine sulphate due to sedative and addictive nature)
- Antisecretory drug- PPI
A 10-month old baby boy develops rapid onset abdominal pain. His mother tells you he has been off his food and not his usual temperament for 3 days prior to this. He is producing regular wet nappies and there are no rashes. He has not vomited however this morning he passed one episode of redcurrent jelly stools. On examination he looks pale and his abdomen there is a sausage shaped mass in the right upper quadrant and the boy draws ups his legs and screams uncontrollably on palpation. What is the most likely diagnosis?
Intussusception - common in infants
screaming
red current jelly stool
‘telescoping of the bowel’
LDH in testicular cancer
good marker of disease progression
AFP in testicular cancer
teratoma
seminoma
hHCG
