Antibodies Flashcards

1
Q

rheumatoid arthritis

A

RF, anti-CCP

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2
Q

SLE

A

ANA, anti-dsDNA, anti-Rho, anti-La

Raised ESR or PV

drug induced: anti-histone

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3
Q

polymyalgia rheumatica

A

ESR or CRP

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4
Q

spondyloarthropathies

A

HLA-B27 gene

Ankylosing spondylitis- raised CRP
Psoriatic arthritis- CRP raised
Reactive arthritis- CRP raised

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5
Q

sjogrens

A

anti-ro and anti la

RF and anti ds-DNA

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6
Q

vasculitis

A

ANA, ANCA, RF

C3, C4

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7
Q

granulomatosis with polyangiitis (Wegeners)

A

cANCA

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8
Q

eosinophilic granulomatosis with polyangiitis (Churg strauss)

A

pANCA

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9
Q

systemic sclerosis

A

limited- Anti-centromere

systemic- scl-70 (topoisomerase)

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10
Q

autoantibodies found in raynauds

A

look for antibodies associated with:

scleroderma, SLE, dermatomyositis and polymyositis, Sjoren’

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11
Q

osteoporosis DEXA

A

-2.50

osteopenia if ,-1-2.5

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12
Q

autoantibody for autoimmune hepatitis

A

anti-smooth muscle

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12
Q

autoantibody for autoimmune hepatitis

A

anti-smooth muscle

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13
Q

autoantibody for autoimmune hepatitis

A

anti-smooth muscle

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14
Q

diffuse systemic scleroderma

A

Scl-70 (topoisomerase) and anti RNA polymerase III

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15
Q

Bowel cancer

A

CEA

16
Q

Pancreatic/ cholangio cancer

A

CA 19-9

17
Q

liver cancer

A

AFP

Alphafetoproetin

18
Q

high output stoma management

A
  • restrict hypotonic solution
  • give dextrose saline
  • Antimotility drug- give loperamide (instead of codeine sulphate due to sedative and addictive nature)
  • Antisecretory drug- PPI
19
Q

A 10-month old baby boy develops rapid onset abdominal pain. His mother tells you he has been off his food and not his usual temperament for 3 days prior to this. He is producing regular wet nappies and there are no rashes. He has not vomited however this morning he passed one episode of redcurrent jelly stools. On examination he looks pale and his abdomen there is a sausage shaped mass in the right upper quadrant and the boy draws ups his legs and screams uncontrollably on palpation. What is the most likely diagnosis?

A

Intussusception - common in infants
screaming
red current jelly stool

‘telescoping of the bowel’

20
Q

LDH in testicular cancer

A

good marker of disease progression

21
Q

AFP in testicular cancer

A

teratoma

22
Q

seminoma

A

hHCG