Antibodies Flashcards
rheumatoid arthritis
RF, anti-CCP
SLE
ANA, anti-dsDNA, anti-Rho, anti-La
Raised ESR or PV
drug induced: anti-histone
polymyalgia rheumatica
ESR or CRP
spondyloarthropathies
HLA-B27 gene
Ankylosing spondylitis- raised CRP
Psoriatic arthritis- CRP raised
Reactive arthritis- CRP raised
sjogrens
anti-ro and anti la
RF and anti ds-DNA
vasculitis
ANA, ANCA, RF
C3, C4
granulomatosis with polyangiitis (Wegeners)
cANCA
eosinophilic granulomatosis with polyangiitis (Churg strauss)
pANCA
systemic sclerosis
limited- Anti-centromere
systemic- scl-70 (topoisomerase)
autoantibodies found in raynauds
look for antibodies associated with:
scleroderma, SLE, dermatomyositis and polymyositis, Sjoren’
osteoporosis DEXA
-2.50
osteopenia if ,-1-2.5
autoantibody for autoimmune hepatitis
anti-smooth muscle
autoantibody for autoimmune hepatitis
anti-smooth muscle
autoantibody for autoimmune hepatitis
anti-smooth muscle
diffuse systemic scleroderma
Scl-70 (topoisomerase) and anti RNA polymerase III