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Pharmacology 2 > Antibiotics Protein Synthesis > Flashcards

Antibiotics Protein Synthesis Flashcards

1
Q

Tetracyclines

A 
Bind to 30s unit of ribosome 
Acne,bacteriostatic, lower respiratory tract, chlamydia, malaria
Lymecycline
Doxycycline 
Take with food, not for under 5s/preg
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2
Q

Gentamicin

A 
Binds irreversibly to 30s unit
IV/IM
Severe sepsis, complicated uti, endocarditis
Only aerobic 
Ototoxicity, nephrotoxicity
Monitor bloods
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3
Q

Chloramphenicol

A

50s site of ribosome

Eye drops

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4
Q

Erythromycin

Macrolide

A

Inhibits enzymes in the liver cyp
Use when allergic to penicillin
Broad spectrum
H.pylori

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5
Q

Clarithromycin

Macrolide

A

Synthetic erythromycin with reduced GI side effects

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6
Q

Linezolid

Macrolide

A 
50s ribosome site
Developed from MOAI
Last new abx
Used as last resort gram positive
Blood disorders must monitor blood
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7
Q

Gonorrhoea

A

Inject ceftriaxone + oral azithromycin

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Pharmacology 2 (14 decks)

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