Antibiotics

Question 1

What is the MOA of penicillin?

Answer 1

blocks cross linking via competitive inhibition of the transpeptidase enzyme

Question 2

What is the MOA of cephalosporins?

Answer 2

blocks cross linking via competitive inhibition of the transpeptidase enzyme

Question 3

What is the MOA of Vancomycin?

Answer 3

disrupts peptioglycan cross-linkage

Question 4

What is the MOA of Rifampin?

Answer 4

inhibits RNA transcription by inhibiting RNA polymerase

Question 5

What is the MOA of TMP-SMX?

Answer 5

inhibition with PABA; folic acid synthesis inhibitor

Question 6

What is the gram stain of enterococci?

Answer 6

Gram + cocci

Question 7

What is the gram stain of Listeria monocytogenes?

Answer 7

gram + bacilli

Question 8

An altered D-alanyl-D-alanine of NAM/NAG-peptide confers resistance to which antiobiotic?

Answer 8

Vancomycin

Question 9

What is the MOA of fluoroquinolones?

Answer 9

blocks DNA replication via inhibition of DNA gyrase

Question 10

What is the MOA of aminoglycosides?

Answer 10

binding to the 30s ribosome subunit, leading to the misreading of mRNA

Question 11

[…] binds to the 23S portion of the 50S subunit and acts by preventing the formation of the initiation complex between the the 30S and 50S subunits of the ribosome

Answer 11

Linezolid