ANTIBIOTIC SENSITIVITY TESTING Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What are Antibiotics

A

they are chemical agents that are produced by organisms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the zone of inhibition?

A

It is the effectiveness of a particular antibiotic measured by its presence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the factors of disc-plate technique?

A
  • the rate of diffusion of the drug through the agar
  • size of inoculum
  • rate of growth
  • susceptibilit of the microorganism to the antibiotic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 4 antibiotic discs used for the antibiotic sensitivity testing?

A
  • Tetracycline
  • Polymyxin B
  • Penicillin G
  • Erythromycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the mode of a action for Tetracycline?

A

Prevents binding of tRNA to 70S ribosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the purpose of Penicillin?

A

Inhibits synthesis of peptidoglycan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the Erythromycin action?

A

Inhibits protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the mode of action for Polymyxin B

A

Alters membrane permeability; binds to phospholipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the Streptomycin for?

A

It affects translation by attaching onto bacterial ribosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Differentiate between:
a.) antibiotics and antimicrobial drugs
b.) broad and narrow spectrum antibiotics

A

a.) targets bacteria and used for treating bacterial infections, acts on microbes
b.) targets many, targets few

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What factors influence the size of the zones of inhibition for an antibiotic?

A

the size of the filter paper and incubation temp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly