ANTIBIOTIC MAN Flashcards
What is the treatment for epiglottitis/supraglottitis
ceftriaxone IV
what is considered mild CAP
CURB 65 0-2
what is considered severe CAP
CURB 65 3-5
What is CURB 65
C - new onset confusion U - Urea > 7 R - RR > 30 B - BP < 90 systolic or <60 diastolic 65 - 65+ age
What is the treatment for mild CAP
Amoxicillin PO/IV 5 days Doxycycline PO (if penicillin allergic) IV clarithromycin (NBM)
What is the treatment for severe CAP
Co-amoxiclav IV + doxycycline IV Levofloxacin (if penicillin allergic) Co-amoxiclav IV + clarithromycin IV (NBM)
What do you step down to in severe CAP?
doxycycline PO
what is the total number of days severe CAP and HAP are treated IV/PO
7
What is the treatment for non-severe HAP
Amoxicillin PO + metronidazole (5 days)
Cotrimoxazole PO + metronidazole (if penicillin allergic)
What is the treatment for severe HAP
Amoxicillin IV + Gentamicin IV + Metronidazole IV
(A Good Mix)
Co-trimoxazole IV + Gentamicin IV + metronidazole IV (if penicillin allergic)
What do you step down to in severe HAP
Co-trimoxazole PO + metronidazole
What is the 1st line treatment for COPD
Amoxicillin
What is the 2nd line treatment for COPD
Doxycycline
What is the treatment for non-severe C. Diff infection
metronidazole PO
what is the treatment for severe C. Diff infection
Vancomycin PO/NG +/- Metronidazole IV
What is the treatment for peritonitis/biliary tract/intra-abdominal infection?
What do you step down to?
How long is the treatment for?
IV amoxicillin + gentamicin + metronidazole
IV vancomycin + gentamicin +metronidazole (if penicillin allergic)
Step down: co-trimoxazole PO + metronidazole
7-10 days
what is the treatment for mild SBP
co-trimoxazole PO
what is the treatment for severe SBP
Piperacillin/Tazobactam IV
What is the step down treatment in severe SBP
co-trimoxazole PO
how long is the treatment of SBP
5-7 days
What is the treatment of an unknown source
IV amoxicillin + metronidazole + gentamicin
IV vancomycin + metronidazole + gentamicin (if penicillin allergic)
+ flucloxacillin/vancomycin if staphylococci
what are the rules for treating endocarditis
high doses - IV
long time - 4-6 weeks
drugs must be bactericidal
staph aureus bacteraemia is treated for 2 weeks to prevent native valve endocarditis
what is the treatment of native valve indolent endocarditis (subacute)
A Native American Gentleman
Native valve - Amoxicillin + Gentamicin
What is the treatment of native valve severe sepsis (acute)
flucloxacillin
What is the treatment for prosthetic valve endocarditis/suspected MRSA
Vancomycin + Gentamicin + Rifampicin
Very Good Replacement
What is the treatment for endocarditis caused by Viridans Strep
Benzopenicillin + Gentamicin
What is the treatment for endocarditis in IVDUs
flucloxacillin
What is the treatment of native valve severe sepsis + risk factors for resistant pathogens
vancomycin + meropenem