anti nutritive factors Flashcards

(54 cards)

1
Q

What things can make diagnosing exposure to mycotoxins difficult

A

Suspect feed may already have been consumed
* Large variations in concentrations of antinutritional factors or
mycotoxins – get a feed test if available
* Multiple concurrent factors
* Tempting to blame mycotoxins for poor
livestock growth performance

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2
Q

what are anti-nutritional factors

A

“Any dietary compound that reduces voluntary feed intake of
animals or impairs digestive function or partitioning and
utilization of absorbed nutrients.”

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3
Q

What are mycotoxins

A

secondary metabolites of fungi with the capacity to induce distinct toxic effects in animals and humans

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4
Q

what are the general characteristics of antinutritional factors

A

usually prodcuts of secondary metabolism

present in virtually all plants to some degree

defensive role- protection from herbivores

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5
Q

what are the two classifications of antinutritional factors

A

heat stable

heat labile

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6
Q

what happens to the protease (trypsin) inhibitors in raw soybeans when heat is added

A

heat treatment of soybeans inactivates the inhibitor

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7
Q

What are lectins found in

A

soybeans and pulses

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8
Q

what do lectins do

A

prevent absorption of nutrients in SI

impair growth and cause diarrhea

affects mostly monogastrics

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9
Q

what does moist heat treatment do to lectins

A

it destroys much of the lectin in grain legumes

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10
Q

Gossypol causes what two syndromes in preruminants

A
  1. sudden death syndrome (resembles heart attack)
  2. chronic labored breathing (resembles pneumonia)
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11
Q

What affect does gossypol have on bulls

A

reduced fertility

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12
Q

why can mature cattle tolerate higher levels of gossypol

A

because gossypol binds to soluble proteins in the rumen

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13
Q

what are tannins

A

polyphenolic compounds with the ability to bind and precipitate proteins

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14
Q

Some herbivores also have evolved to produce_______ in their
saliva which bind to tannins during ingestion and reduce biological activity
(deer > goat > sheep > cattle)

A

proline-rich proteins

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15
Q

what affect do tannins have on ruminants

A

reduces RDP and increases RUP

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16
Q

What beneficial affect do tannins have

A

provides protection against bloat

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17
Q

what affect do tannins have non monogastrics

A

reduces DM and protein digestion, voluntary intake and growth

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18
Q

Saponins

A

form stable soap-like forms, impair digestion of protein and uptake of vit and min in gut

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19
Q

what affect does saponins have on ruminants

A

increases bloat

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20
Q

Saponins ____ bloat while tannins _____ decrease bloat

A

saponins increase, tannins decrease

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21
Q

mimosine

A

has metabolic derivative 3,4-DHP, and comes from legume plant Leucaena leucocephala. causes anorexia, reduced growth, goiter, etc

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22
Q

cyanogenic glycosides

A

found in clover, high concentrates associated with N fertilization, immaturity, and frost damage, may cause neurological symptoms

23
Q

phytoestrogens

A

reduce fertility through competitive inhibition of estrogen.

24
Q

the main source of phytoestrogen is

25
Plant breeders have developed ______ of subterranean clover, greatly reducing animal losses due to phytoestrogens
low-estrogen cultivars
26
oxalate
promotes formation of kidney stones.
27
what causes secondary nutritional hyperparathyroidism
oxalate
28
what are two sources of oxalate
rhubarb leaves, or kochia
29
what does oxalate posioning resemble
antifreeze poisoning
30
glucosinolates
contain toxin s-methylcysteine sulfoxide (SMCSO)
31
what is SMCSO also known as
"brassica anemia factor"
32
how do mycotoxins exert their effects
Reduced intake or feed refusal * Reduced nutrient absorption and impaired metabolism * Altered endocrine or exocrine systems * Suppressed immune function * Altered rumen microbial growth
33
what are the most prevalent mycotoxins in canada
Most prevalent in Canada are Fusarium toxins and ergot alkaloids
34
what are the three primary infleunces of mold growth
mositure, temperature, oxygen level
35
aflatoxin
carcinogenic. corn, peanuts, peanut meal. causes liver damage and accumulates in liver
36
what clinical signs does aflatoxin have in cattle
diarrhea, severe tenesmus, pale enlargd fatty livers
37
what clinical signs does aflatoxin have in pigs
anorexia, weight loss, tremours, hemorrhagic diarrhea
38
fumonisin B1 and B2 cause what in horses
equine leukoencephalomalacia
39
fumonisin B1 and B2 cause what in pigs
porcine pulmonary edema (PPE) and abortion
40
vomitoxins are particularly dangerous to what species
swine
41
zearlaenone is a ____ mycotoxin
estrogen-like
42
T/F zearalenone affects feed intake
false
43
what species is particularly sensitive to zearalenone
swine
44
what problems does zearalenone cause
reproductive problems
45
T2 toxin in cattle
Gastroenteritis, intestinal hemorrhage, abomasal and ruminal ulcers, death
46
T2 toxin in pigs
potent immunosuppressive agent
47
ochratoxin A is a ____ toxin that causes ____
renal, PUPD
48
Ergot affects which two grains the most
rye and triticale
49
what is ergotism
Caused by ingestion of infected pasture, hayor cereal kernels * Disease-causing agents are alkaloids within the ergot bodies * Cattle, sheep, pigs, horses,dogs and birds can be affected; * Toxic component is preserved during ensiling
50
what are ergot alkaloids
stable version of ergot, hard to break down
51
ergotism in cattle
Gangrene of the extremities due to vasoconstriction, agalactia, low conception rates,abortion
52
what hormone does Ergotism mess with
prolactin
53
ergotism in pigs
agalactia due to lack of prolactin, neonatal mortality, gangrene on ear and tail
54