Anti-Emetics Flashcards
Reglan
Another Name
Metoclopramide
Metoclopramide
Another Name
Reglan
Reglan (Metoclopramide)
Class
Antiemetic
Reglan (Metoclopramide)
Description
dopamine antagonist similar to procainamide but with few antidysrhythmic or anesthetic properties. Its antiemetic properties stem from rapid gastric emptying and desensitization of vomiting reflex.
Reglan (Metoclopramide)
Indications
Nausea and Vomiting
Reglan (Metoclopramide)
Contraindication
hypersensitivity, seizure disorders, GI obstruction or perforation, breast cancer
Reglan (Metoclopramide)
Precautions
CHF, hypokalemia, renal impairment, GI hemorrhage, intermittent porphyria
Reglan (Metoclopramide)
Dose/Route
10-20 mg IM; 10 mg slow IV (over 2-4 min)
Pedi 1-2 mg/kg/dose
Promethazine
Another Name
Phenergan
Phenergan
Another Name
Promethazine
Promethazine (Phenergan)
Class
Antiemetic
Promethazine (Phenergan)
Description
anticholinergic agent that enhances the effects of analgesics and potent antiemetic
Promethazine (Phenergan)
Indications
Nausea and vomiting, motion sickness, enhance effects of analgesics and induce sedation
Promethazine (Phenergan)
Contraindications
None
Promethazine (Phenergan)
Precautions
hepatic, respiratory, or cardiac impairment, asthma, hypertension, elderly or debilitated pts
Promethazine (Phenergan)
Dose/Route
12.5-25mg IV/IM/PR
Pedi: 0.5 mg/kg IV/IM/PR
Compazine (Prochlorperzine)
Class
Antiemetic
Zofran
Class
Antiemetic
Zofran
Description
selective blocking agent of the serotonin 5-HT3 receptor type
Zofran
Indication
Prevention of nausea and intractable vomiting
Zofran
Contraindication
None
Zofran
Precautions
may mask a progressive ileus and/or gastric distension,
Long QT syndrome
Zofran
Dose/Route
4 mg IVP or single 4 mg tablet ODT
