Anti-Emetics Flashcards

1
Q

Reglan

Another Name

A

Metoclopramide

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2
Q

Metoclopramide

Another Name

A

Reglan

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3
Q

Reglan (Metoclopramide)

Class

A

Antiemetic

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4
Q

Reglan (Metoclopramide)

Description

A

dopamine antagonist similar to procainamide but with few antidysrhythmic or anesthetic properties. Its antiemetic properties stem from rapid gastric emptying and desensitization of vomiting reflex.

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5
Q

Reglan (Metoclopramide)

Indications

A

Nausea and Vomiting

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6
Q

Reglan (Metoclopramide)

Contraindication

A

hypersensitivity, seizure disorders, GI obstruction or perforation, breast cancer

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7
Q

Reglan (Metoclopramide)

Precautions

A

CHF, hypokalemia, renal impairment, GI hemorrhage, intermittent porphyria

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8
Q

Reglan (Metoclopramide)

Dose/Route

A

10-20 mg IM; 10 mg slow IV (over 2-4 min)

Pedi 1-2 mg/kg/dose

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9
Q

Promethazine

Another Name

A

Phenergan

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10
Q

Phenergan

Another Name

A

Promethazine

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11
Q

Promethazine (Phenergan)

Class

A

Antiemetic

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12
Q

Promethazine (Phenergan)

Description

A

anticholinergic agent that enhances the effects of analgesics and potent antiemetic

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13
Q

Promethazine (Phenergan)

Indications

A

Nausea and vomiting, motion sickness, enhance effects of analgesics and induce sedation

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14
Q

Promethazine (Phenergan)

Contraindications

A

None

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15
Q

Promethazine (Phenergan)

Precautions

A

hepatic, respiratory, or cardiac impairment, asthma, hypertension, elderly or debilitated pts

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16
Q

Promethazine (Phenergan)

Dose/Route

A

12.5-25mg IV/IM/PR

Pedi: 0.5 mg/kg IV/IM/PR

17
Q

Compazine (Prochlorperzine)

Class

A

Antiemetic

18
Q

Zofran

Class

A

Antiemetic

19
Q

Zofran

Description

A

selective blocking agent of the serotonin 5-HT3 receptor type

20
Q

Zofran

Indication

A

Prevention of nausea and intractable vomiting

21
Q

Zofran

Contraindication

A

None

22
Q

Zofran

Precautions

A

may mask a progressive ileus and/or gastric distension,

Long QT syndrome

23
Q

Zofran

Dose/Route

A

4 mg IVP or single 4 mg tablet ODT