anti arrhythmic med

Question 1

Example of class IA med

Answer 1

disopyramide

Question 2

mechanisms of disopyramide

Answer 2

targets voltage activated Na+ channel, moderate rate of dissociation. Slows the rate of rising action potential, prolongs refractory period

Question 3

example of class IB med

Answer 3

Lignocaine

Question 4

Mechanisms of lignocaine

Answer 4

targets voltage activated Na+ channels, fast rate of dissociation, prevents premature beats

Question 5

Example of class IC med

Answer 5

Flecainide

Question 6

Mechanisms of flecainide

Answer 6

targets voltage activated Na+ channels, slow dissociation, depresses conduction

Question 7

Example of class II med

Answer 7

beta blocker- metoprolol

Question 8

Example of class III med

Answer 8

amiodarone

Question 9

Mechanisms of metoprolol

Answer 9

works as a beta antagonsit on the beta adrenoceptors, decreasing rate of depolarisation in SA and AV nodes

Question 10

Mechanisms of amiodarone

Answer 10

targets voltage activated K+ channels, prolonging action potential duration, increasing refractory period

Question 11

what should not be prescribed along side amiodarone?

Answer 11

digoxin

Question 12

Example of class IV med

Answer 12

non selective/ rate limiting CCB (verapamil)

Question 13

mechanisms of verapamil

Answer 13

it blocks the voltage activated Ca2+ channel, slowing rate of dissociation, preventing premature beats